Human Scf manufacturers
- Albumins, human
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- $500.00 / 1KG
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2021-09-07
- CAS:70024-90-7
- Min. Order: 1KG
- Purity: >99%
- Supply Ability: 5000kg/month
- GALANIN, HUMAN
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- $7.00 / 1KG
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2020-02-13
- CAS:119418-04-1
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 100KG
- GIP (HUMAN)
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- $7.00 / 1KG
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2020-02-12
- CAS: 100040-31-1
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 100KG
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| Human Scf Basic information |
Product Name: | Human Scf | Synonyms: | RHSCF;RECOMBINANT HUMAN SCF;REC STEM CELL FACTOR (HUMAN);REC SCF (HUMAN);SCF, HUMAN;STEM CELL FACTOR, HUMAN;STEM CELL FACTOR, HUMAN, RECOMBINANT;STEM CELL FACTOR, HUMAN, RECOMBINANT, E COLI | CAS: | 133352-98-4 | MF: | | MW: | 0 | EINECS: | | Product Categories: | | Mol File: | Mol File | |
| Human Scf Chemical Properties |
storage temp. | −20°C | form | powder |
Hazard Codes | Xi | Risk Statements | 36/38 | Safety Statements | 26 | WGK Germany | 3 | HS Code | 2937190000 |
| Human Scf Usage And Synthesis |
General Description | The KITLG (KIT ligand) gene is mapped to human chromosome 12q21.32. | Biochem/physiol Actions | Stem Cell Factor (SCF), also known as c-Kit ligand (KL), steel factor (SLF) and mast cell growth factor (MGF), is a 30 kDa glycoprotein with broad activities on various tissues, including hematopoietic cells, pigment cells, and primordial germ cells. SCF is secreted by endothelial cells, fibroblasts, and bone marrow stromal cells as a membrane-bound form which may be cleaved to release the soluble form. Both forms are active in promoting colony formation from murine bone marrow cells, but membrane-bound SCF is more effective in promoting hematopoieses in vivo, suggesting a role in cellular interactions between hematopoietic and stromal cells. The soluble is thought to exist in solution as a noncovalently linked dimer. SCF is structurally related to M-CSF (CSF-1) and Flt-3/Flk-2 Ligand (FL) with all three sharing a similar size, existence of transmembrane and soluble forms, four conserved cysteines, and alternative splicing exon locations, but they share little sequence homology. SCF alone is a modest colony stimulating factor. However, in the presence of other cytokines such as EPO, TPO, GM-CSF, G-CSF, M-CSF, IL-3, and IL-7, SCF is a potent costimulant that works synergistically to increase the size of myeloid, erythroid or lymphoid lineage colonies without influencing the lineage differentiation of the progenitors. |
| Human Scf Preparation Products And Raw materials |
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