| Company Name: |
AHH Chemical Co,.Ltd
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| Tel: |
86-1860259310 |
| Email: |
sales@ahhchemical.com |
| Products Intro: |
Cas:
ProductName:sterol;Cholesterin,Cholest-5-en-3beta-ol
Brand：ahhchemical | Product Number：MT-58746 | Purity：98%
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Question and answer - Q:Understanding of Cholesterol
- A:Cholesterol is a waxy, fat-like substance that's found in all the cells in your body. Your body needs some cholesterol to make....
- Nov 15，2019
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| | Cholesterin Chemical Properties |
| Melting point | 148-150 °C | | alpha | -36 º (c=2, dioxane) | | Boiling point | 360 °C | | density | 1.06 | | refractive index | 1.5250 (estimate) | | Fp | 250 °C | | storage temp. | -20°C | | solubility | H2O: 0.002 mg/mL | | pka | 15.03±0.70(Predicted) | | form | powder | | Specific Gravity | 1.067 | | color | white | | Odor | wh. or faintly yel. pearly granules or crystals, almost odorless | | Water Solubility | negligible | | Merck | 14,2201 | | BRN | 1915888 | | Dielectric constant | 2.9（Ambient） | | InChIKey | HVYWMOMLDIMFJA-DPAQBDIFSA-N | | LogP | 9.619 (est) | | CAS DataBase Reference | 57-88-5(CAS DataBase Reference) | | IARC | 3 (Vol. 31, Sup 7) 1987 | | NIST Chemistry Reference | Cholesterol(57-88-5) | | EPA Substance Registry System | Cholesterol (57-88-5) |
| Hazard Codes | Xn,Xi | | Risk Statements | 10-48/20/22-40-38-22-36/37/38-67-36/38-20-63 | | Safety Statements | 24/25-22-36/37-36-26 | | RIDADR | UN 1170 3/PG 3 | | WGK Germany | 1 | | RTECS | FZ8400000 | | TSCA | Yes | | HS Code | 2906 13 10 | | HazardClass | IRRITANT | | Hazardous Substances Data | 57-88-5(Hazardous Substances Data) | | Toxicity | Present in all
parts of the animal body; concentrated in spinal cord, brain, skin
secretions, and gallstones. An unsaturated, unsaponifiable alcohol
(m.p. 149℃). It is synthesized in the body from ethanoate units;
its metabolism is regulated by a specific set of enzymes. It is the
parent compound of many other steroids and its presence in high
concentrations in the blood is suspected as being a contributory
factor in cardiovascular disease. |
| | Cholesterin Usage And Synthesis |
| Description |
As cholesterin seems to be a constituent of most if not all cells, it may be assumed that it is of some importance, even though the quantity is generally small, yet to this time its real purpose has remained practically unknown.
| | Occurrence |
Cholesterin is widely found and distributed in animal bodies, and is especially most abundant in the brain and nerve tissue. It also has high content in the kidney, spleen, skin, liver and bile. The solubility of cholesterin is similar to that of the fat which is insoluble in water, but easily soluble in ether, chloroform and some other solvents.
| | Biological Functions | The main physiological function of cholesterin participating in forming cell membranes, myelin, brain, and can be further converted to bile acids and steroid hormones. There are two major lipoproteins which are involved in cholesterin transport: the low density lipoprotein (LDL) and high density lipoprotein (HDL). The former can transport cholesterol from the liver to the cells of whole body tissues, while the later one transports cholesterol from tissue cells back into the liver.
| | Chemical Reactivity | Chemically, cholesterin is one of the most inert of the body constituents, and it seems improbable that it plays any part in metabolic processes, for which reason there have been those who have been content to consider cholesterin as merely a by-product in cell metabolism, which was present in the cells in recognizable quantities, chiefly because its resistance to alteration made its removal slow.
| | Side effects |
The cholesterol level in the blood can reflect the overall metabolism condition of cholesterol. The total cholesterol content in the blood plasma of normal adult of empty stomach is about 2.83~5.17mmol/L. Abnormal cholesterol metabolism could easily lead to deposition of cholesterol in the blood vessel wall, forming atherosclerosis, causing coronary heart disease and stroke.
| | Physiological effects | Cholesterin is closely related to the body tissues, bile acids and hormones. It is an indispensable substance of animal tissue cells, which is not only involved in the formation of cell membranes, but also as the precursor for the synthesis of bile acids, steroid hormones and vitamin D3.
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| | Cholesterin Preparation Products And Raw materials |
| Raw materials | Ethanol | | Preparation Products | Lecithin-->Cholesteryl acetate-->Dehydroepiandrosterone-->PHOSPHATIDYLETHANOLAMINE-->Atificial Cow-bezoar-->STREPTOKINASE-->7-Dehydrocholesterol-->Cholesteryl benzoate-->Androsta-1,4-diene-3,17-dione-->Nuclease, streptococcal deoxyribo--->CHOLESTERYL HYDROGEN SUCCINATE-->3-hydroxy-5-oxo-5,6-secocholestan-6-al-->CHOLESTEROL-5ALPHA,6ALPHA-EPOXIDE-->20ALPHA-HYDROXYCHOLESTEROL-->LATHOSTEROL-->[(3S,9S,10R,13R,14S,17R)-10,13-Dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl] decanoate |
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