| Company Name: |
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| Tel: |
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| Email: |
kapil@ultrachem.co.in |
| Products Intro: |
Cas:9005-70-3
ProductName:Polysorbate-80
Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
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| Company Name: |
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| Tel: |
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| Email: |
mail@choicechemicals.in |
| Products Intro: |
Cas:9005-70-3
ProductName:Polysorbate
Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
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| Company Name: |
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| Tel: |
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| Email: |
vasudha@vasudhachem.com |
| Products Intro: |
Cas:9005-70-3
ProductName:Polysorbate 85
Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
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- Polysorbate 80
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- $1.80/ kg
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2024-09-11
- CAS:9005-70-3
- Min. Order: 1000kg
- Purity: 80%
- Supply Ability: 600 tons
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| | Polysorbate 80 Basic information |
| Product Name: | Polysorbate 80 | | Synonyms: | polyoxyethylene20sorbitaltrioleate;protasorbto-20;sorbimacrogoltrioleate300;sorbitan,trioleatepolyoxyethylenederiv.;tri-9-octadecenoate,poly(oxy-1,2-ethanediyl)derivs.,(z,z,z)-sorbita;tri-9-octadecenoate,poly(oxy-1,2-ethanediyl)derivs.,(Z,Z,Z)-Sorbitan;Polyethylene glycol sorbitan trioleate, Polyoxyethylene sorbitantrioleate;Polyoxyethylene (20) sorbitan trioleate, Polyoxyethylenesorbitan Trioleate | | CAS: | 9005-70-3 | | MF: | CH4 | | MW: | 16.04246 | | EINECS: | 618-422-4 | | Product Categories: | Biochemistry;Nonionic Surfactants (for Biochemistry);Surfactants (for Biochemistry);Ester Ether Type (Surfactants);Functional Materials;Nonionic Surfactants;Surfactants | | Mol File: | 9005-70-3.mol |  |
| | Polysorbate 80 Chemical Properties |
| Melting point | -20 °C | | Boiling point | 100 °C | | density | 1.028 g/mL at 20 °C | | vapor pressure | <1 mm Hg ( 20 °C) | | refractive index | n20/D 1.473 | | Fp | >230 °F | | storage temp. | Store below +30°C. | | solubility | Dispersible in water, in anhydrous ethanol, in ethyl acetate and in methanol, practically insoluble in fatty oils and in liquid paraffin. | | form | viscous liquid | | Specific Gravity | 1.030 (20/4℃) | | color | Light yellow to Brown | | Hydrophilic-Lipophilic Balance (HLB) | 11 | | InChI | InChI=1S/CH4/h1H4 | | InChIKey | VNWKTOKETHGBQD-UHFFFAOYSA-N | | SMILES | C | | EPA Substance Registry System | Polysorbate 85 (9005-70-3) |
| Safety Statements | 24/25 | | WGK Germany | 1 | | RTECS | WG2934000 | | F | 3 | | HS Code | 34021300 | | Toxicity | LD50 orally in Rabbit: > 36000 mg/kg |
| | Polysorbate 80 Usage And Synthesis |
| Description | Polysorbate 80, a surfactant, has been widely used as a solvent for pharmacological experiments. Tween 80 can also reduce bacterial attachment and inhibit biofilm formation. | | Definition | DrugBank: Polysorbate 80 is a hydrophilic nonionic surfactant. It is utilized as a surfactant in soaps and cosmetics and also as a lubricant in eye drops. In food or pharmaceutical products, it can act as an emulsifier. Polysorbate 80 is an excipient that is used to stabilize aqueous formulations of medications for parenteral administration or vaccinations. A solubilizing agent acts as a surfactant and increases the solubility of one agent in another. A substance that would not normally dissolve in a particular solution is able to dissolve with the use of a solubilizing agent. It is also known as an emulsifier, which helps ingredients mix together and prevent separation, and water-containing small amounts of salts, and is included in several vaccines licensed in the USA. | | Biochem/physiol Actions | Polysorbate 80 has low-grade toxicity in both mice and rats when administered by the intraperitoneal and oral routes, producing mild to moderate depression of the central nervous system, significant reductions in locomotor activity and rectal temperatures, demonstration of ataxia and paralysing activity, and enhancement of pentobarbital sleep duration.
It had a dose-dependent antihypertensive effect in dogs administered intravenously.
Polysorbate 80 had no direct stimulatory or relaxant effect on the guinea-pig ileum or rat uterus, but it antagonised contractions induced by acetylcholine, histamine, barium, 5-hydroxytryptophan and carbachol in a dose-dependent manner.
A direct relaxant effect was observed on rabbit jejunum. Dose-dependent myocardial inhibition was observed on guinea pig and rabbit paired atrial preparations. In electrically driven guinea pig left atrial preparations, it exhibited a dose-dependent negative inotropic effect. It does not induce diuresis in rats below a dose of 2.5 ml/kg. |
| | Polysorbate 80 Preparation Products And Raw materials |
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