- ST1481
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- $1.00 / 1g
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2020-01-09
- CAS:292618-32-7
- Min. Order: 1g
- Purity: 99%
- Supply Ability: 200kg
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Product Name: | ST1481 | Synonyms: | GIMATECAN;ST1481;ST1481: GIMATECAN;(4S)-11-((E)-((1,1-Dimethylethoxy)imino)methyl)-4-ethyl-4-hydroxy-1,12-dihydro-14H-pyrano(3',4':6,7)indolizino(1,2-b)quinoline-3,14(4H)-dione;1H-Pyrano(3',4':6,7)indolizino(1,2-B)quinoline-11-carboxaldehyde, 4-ethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-, 11-(o-(1,1-dimethylethyl)oxime), (C(E),4S)-;7-T-Butoxyiminomethylcamptothecin;Lbq707;Unii-7kks9R192f | CAS: | 292618-32-7 | MF: | C25H25N3O5 | MW: | 447.488 | EINECS: | | Product Categories: | | Mol File: | 292618-32-7.mol | ![ST1481 Structure](CAS/GIF/292618-32-7.gif) |
| ST1481 Chemical Properties |
Boiling point | 780.6±70.0 °C(Predicted) | density | 1.37±0.1 g/cm3(Predicted) | storage temp. | Store at -20°C | pka | 11.20±0.20(Predicted) | form | Solid | color | Light yellow to yellow |
| ST1481 Usage And Synthesis |
Biological Activity | Gimatecan (ST1481) is a potent topoisomerase I inhibitor. It is an orally active camptothecin analog with antineoplastic activity. | in vivo | Gimatecan (2 mg/kg; treatment per os, every fourth day for four times) is effective for inhibiting tumor growth. < div class="cpd-mod-vv"> Animal Model: | Athymic Swiss nude mice bearing HT1376 model | Dosage: | 2 mg/kg | Administration: | Treatment per os, every fourth day for four times | Result: | Caused a marked tumor growth inhibition during treatment. | table> target | |
| ST1481 Preparation Products And Raw materials |
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Tag:ST1481(292618-32-7)
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