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| | 4-Amidinophenylmethanesulfonyl fluoride hydrochloride Basic information |
| Product Name: | 4-Amidinophenylmethanesulfonyl fluoride hydrochloride | | Synonyms: | APMSF HCL;APMSF HYDROCHLORIDE;4-AMIDINOPHENYLMETHANESULFONYL FLUORIDE HYDROCHLORI;P-APMSF;P-APMSF, HYDROCHLORIDE;(P-AMIDINOPHENYL)METHANESULFONYL FLUORIDE HYDROCHLORIDE;P-AMIDINOPHENYLMETHYLSULFONYLFLUORIDE, HCL;P-AMIDINOPHENYLMETHYL-SULFONYLFLUORIDE HYDROCHLORIDE | | CAS: | 74938-88-8 | | MF: | C8H10ClFN2O2S | | MW: | 252.69 | | EINECS: | | | Product Categories: | inhibitor | | Mol File: | 74938-88-8.mol |  |
| | 4-Amidinophenylmethanesulfonyl fluoride hydrochloride Chemical Properties |
| Melting point | ~205 °C (dec.) | | storage temp. | -20°C | | solubility | H2O: 50 mM Stable when aliquoted at −20°C. Half-life = 6 minutes in pH 7.0 buffer systems. | | form | White solid | | BRN | 9083148 | | InChIKey | KHLLRHIUKOJXLL-UHFFFAOYSA-N | | CAS DataBase Reference | 74938-88-8(CAS DataBase Reference) |
| | 4-Amidinophenylmethanesulfonyl fluoride hydrochloride Usage And Synthesis |
| Description | p-APMSF is an irreversible inhibitor of serine proteases with Ki values of 1.02, 1.18, 1.5, and 1.54 μM for bovine trypsin, human thrombin, bovine plasmin, and bovine Factor Xa, respectively. It is selective for these proteases over bovine chymotrypsin and acetylcholinesterase. | | Biochem/physiol Actions | Irreversible inhibitor of serine proteases with lysine or arginine substrate specificities. Effective concentration 10-100 μM. Frequently used to characterize newly discovered proteases. |
| | 4-Amidinophenylmethanesulfonyl fluoride hydrochloride Preparation Products And Raw materials |
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