Mitoguazone manufacturers
- Mitoguazone
-
- $10.00 / 1KG
-
2025-04-16
- CAS:459-86-9
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 10 mt
- Mitoguazone
-
- $300.00/ kg
-
2025-03-07
- CAS:459-86-9
- Min. Order: 1kg
- Purity: 99.5%(HPLC)
- Supply Ability: 10 tons
- Mitoguazone USP/EP/BP
-
- $1.10 / 1g
-
2021-07-03
- CAS:
- Min. Order: 1g
- Purity: 99.9%
- Supply Ability: 100 Tons Min
|
| | Mitoguazone Basic information |
| Product Name: | Mitoguazone | | Synonyms: | 1,1'-((methylethanediylidene)dinitrilo)di-guanidin;1,1'-((methylethanediylidene)dinitrilo)diguanidine;2,2'-(1-methyl-1,2-ethanediylidene)bis-hydrazinecarboximidamid;methyl-g;methyl-gag;2,2'-(1-Methyl-1,2-ethanediylidene)bis(hydrazinecarbimidamide);Me-GAG;MGBG | | CAS: | 459-86-9 | | MF: | C5H12N8 | | MW: | 184.2 | | EINECS: | 202-958-7 | | Product Categories: | | | Mol File: | 459-86-9.mol |  |
| | Mitoguazone Chemical Properties |
| Melting point | 225 °C (decomp) | | Boiling point | 323.8±25.0 °C(Predicted) | | density | 1.55±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | pka | 7.63, 9.05(at 25℃) | | form | Solid | | color | Light brown to brown | | Water Solubility | Water: 50 mg/mL (271.44 mM; ultrasonic and adjust pH to 9 with HCl) | | CAS DataBase Reference | 459-86-9 |
| | Mitoguazone Usage And Synthesis |
| Uses | Mitoguazone has therapeutic applications as a cytotoxic agent. | | Definition | ChEBI: A hydrazone obtained by formal condensation of the two carbonyl groups of methylglyoxal with the primary amino groups of two molecules of aminoguanidine. | | in vivo | The influence of different stages of leukemia P388 on the pharmacokinetics of the antineoplastic agent Mitoguazone in mice is investigated. Independent of the tumor stage investigated, the total clearance of mitoguazone is slightly reduced reflecting a moderate increase of AUC in the serum of leukemia-bearing animals. Furthermore, in an advanced tumor stage the drug levels in kidneys, liver, spleen and serum are found to be elevated to some extent in comparison to tumor-free controls in contrast to an earlier stage of leukemia[5]. |
| | Mitoguazone Preparation Products And Raw materials |
|