Company Name: |
Tianjin Kailiqi Biotechnology Co., Ltd.
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Tel: |
15076683720 |
Email: |
klq@cw-bio.com |
Products Intro: |
Product Name:YM17E CAS:124900-72-7 Purity:≥98% Package:1g,5g,10g,25g根据客户需要分装 Remarks:Not For Human Use, Lab Use Only.
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Company Name: |
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
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Tel: |
18818260767 |
Email: |
sales@chemegen.com |
Products Intro: |
Product Name:YM17E CAS:124900-72-7 Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
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Product Name: | YM17E | Synonyms: | YM17E;Urea, N,N''-[1,3-phenylenebis(methylene)]bis[N-cycloheptyl-N'-[4-(dimethylamino)phenyl]- (9CI);Diglyceride acyltransferase,Inhibitor,acyl-CoA:cholesterol acyltransferase,inhibit,YM17E,Acyltransferase,Diacylglycerol acyltransferase,mono- acylglycerol acyltransferase,YM-17E;1,1'-(1,3-Phenylenebis(methylene))bis(1-cycloheptyl-3-(4-(dimethylamino)phenyl)urea);1,1'-(1,3-Phenylenebis(methylene))bis(1-cycloheptyl-3-(4-(dimethylamino)phenyl)urea) | CAS: | 124900-72-7 | MF: | C40H56N6O2 | MW: | 652.93 | EINECS: | | Product Categories: | | Mol File: | 124900-72-7.mol | |
| YM17E Chemical Properties |
Boiling point | 862.7±65.0 °C(Predicted) | density | 1.16±0.1 g/cm3(Predicted) | storage temp. | Store at -20°C | solubility | Soluble in DMSO | form | Solid | pka | 14.03±0.70(Predicted) | color | White to off-white |
| YM17E Usage And Synthesis |
Biological Activity | YM17E is an inhibitor of acyl-CoA:cholesterol acyltransferase (ACAT) with IC50 of 44 nM in vitro in rabbit liver microsomes. | in vitro | YM17E is as potent in inhibiting ACAT activity in the liver as in the intestine, with IC 50 values of 45 and 34 nM, respectively. | target | IC50: 44 nM (ACAT in rabbit liver microsomes) |
| YM17E Preparation Products And Raw materials |
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