Log in | Join Free | china | japan | germany

3,6-DICHLORO-BENZO[B]THIOPHENE-2-CARBOXYLIC ACID

Request For Quotation
3,6-DICHLORO-BENZO[B]THIOPHENE-2-CARBOXYLIC ACID Suppliers list
Company Name: career henan chemical co
Tel: +86-0371-86658258 +8613203830695
Email: sales@coreychem.com
Products Intro: Product Name:3,6-DICHLORO-BENZO[B]THIOPHENE-2-CARBOXYLIC ACID
CAS:34576-94-8
Purity:96% Package:1KG;1USD
Company Name: Chongqing Chemdad Co., Ltd
Tel: +86-023-6139-8061 +86-86-13650506873
Email: sales@chemdad.com
Products Intro: Product Name:3,6-DICHLORO-BENZO[B]THIOPHENE-2-CARBOXYLIC ACID
CAS:34576-94-8
Purity:0.98 Package:1kg，2kg，5kg，10kg，25kg
Company Name: CONIER CHEM AND PHARMA LIMITED
Tel: +8618523575427
Email: sales@conier.com
Products Intro: Product Name:3,6-dichlorobenzo[b]thiophene-2-carboxylic acid
CAS:34576-94-8
Package:100g,1kg
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Products Intro: Product Name:BT2
CAS:34576-94-8
Purity:98.00% Package:10 mg；50 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: InvivoChem
Tel: +1-708-310-1919 +1-13798911105
Email: sales@invivochem.cn
Products Intro: Product Name:BT2
CAS:34576-94-8
Purity:98% Package:10mg Remarks:V17161

3,6-DICHLORO-BENZO[B]THIOPHENE-2-CARBOXYLIC ACID manufacturers
3,6-DICHLORO-BENZO[B]THIOPHENE-2-CARBOXYLIC ACID Basic information
Product Name:3,6-DICHLORO-BENZO[B]THIOPHENE-2-CARBOXYLIC ACID
Synonyms:3,6-dichloro-2-benzothiophenecarboxylic acid;3,6-dichlorobenzothiophene-2-carboxylic acid;BT2;JR-6478, 3,6-Dichlorobenzo[b]thiophene-2-carboxylic acid, 97%;Benzo[b]thiophene-2-carboxylic acid, 3,6-dichloro-;3,6-Dichloro-1-benzothiophene-2-carboxylicaci;3,6-DICHLORO-BENZO[B]THIOPHENE-2-CARBOXY;Bcl-2 Family,BT2,Inhibitor,BT-2,inhibit,BT 2
CAS:34576-94-8
MF:C9H4Cl2O2S
MW:247.1
EINECS:
Product Categories:
Mol File:34576-94-8.mol
3,6-DICHLORO-BENZO[B]THIOPHENE-2-CARBOXYLIC ACID Structure
3,6-DICHLORO-BENZO[B]THIOPHENE-2-CARBOXYLIC ACID Chemical Properties
Boiling point 426.4±40.0 °C(Predicted)
density 1.653±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility Soluble in DMSO (up to at least 20 mg/ml)
form solid
pka2.09±0.30(Predicted)
color Off-white
Stability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Safety Information
MSDS Information
3,6-DICHLORO-BENZO[B]THIOPHENE-2-CARBOXYLIC ACID Usage And Synthesis
Description3,6-dichloro-benzo[b]thiophene-2-Carboxylic acid is an inhibitor of myeloid cell leukemia 1 (Mcl-1) with a Ki value of 59 μM for binding of FITC-Mcl-1-BH2 peptide binding to Mcl-1. It has been used as a building block in the synthesis of inhibitors of Mcl-1, the toll-like receptor 3/double-stranded RNA (TLR3/dsRNA) complex, and D-amino acid oxidase (DAO).
References1) Tso et al. (2014), Benzothiophene carboxylate derivatives as novel allosteric inhibitors of branched-chain α-ketoacid dehydrogenase kinase; J. Biol. Chem., 289 20583 2) Friberg et al. (2013), Discovery of potent myeloid cell leukemia (Mcl 1) inhibitors using fragment based methods and structure based design; J. Med. Chem. 56 15
3,6-DICHLORO-BENZO[B]THIOPHENE-2-CARBOXYLIC ACID Preparation Products And Raw materials
Tag:3,6-DICHLORO-BENZO[B]THIOPHENE-2-CARBOXYLIC ACID(34576-94-8) Related Product Information
ZM 447439 TYRPHOSTIN AG 879 2,4-Thiazolidinedione,5-(1,3-benzodioxol-5-ylmethylene)- AAL-993 Biphenyl-4,4'-dicarboxylic acid Indole 3,4,6-TRICHLORO-1-BENZOTHIOPHENE-2-CARBOXYLIC ACID ETHYL 3,6-DICHLORO-1-BENZOTHIOPHENE-2-CARBOXYLATE 3,6-DICHLORO-BENZO[B]THIOPHENE-2-CARBOXYLIC ACID METHYL 3 6-DICHLOROBENZO(B)THIOPHENE-2-& METHYL 3,4,6-TRICHLOROBENZO[B]THIOPHENE-2-CARBOXYLATE 3,4,6-trichloro-7-fluorobenzo[b]thiophene-2-carboxylic acid