- Anethol Trithione
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- $0.00 / 25Kg/Bag
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2024-12-25
- CAS:532-11-6
- Min. Order: 2Kg/Bag
- Purity: 0.99
- Supply Ability: 20 tons
- Anethole trithione
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- $10.00 / 1KG
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2024-11-29
- CAS:532-11-6
- Min. Order: 100KG
- Purity: 99%
- Supply Ability: 100 mt
- Anethole trithione
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- $90.00 / 500mg
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2024-11-19
- CAS:532-11-6
- Min. Order:
- Purity: 99.65%
- Supply Ability: 10g
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| Product Name: | Anethole trithione | | Synonyms: | Anetholi Trithionum;5-(4-methoxyphenyl)dithiole-3-thione;(E)-O-4-(prop-1-enyl)-5,6-dithioxocyclohexa-1,3-dienyl methanethioate;4-(prop-1-en-1-yl)-5,6-disulfanylidenecyclohexa-1,3-dien-1-yl carbothioate;Anethol trithione ,5-(4-Methoxyphenyl)-1,2-dithiole-3-thione;Anethali Trithinum;ANETHOLE TRITHIONE;5-(4-methoxyphenyl)-3h-1,2-dithiole-3-thione | | CAS: | 532-11-6 | | MF: | C10H8OS3 | | MW: | 240.36 | | EINECS: | 208-528-5 | | Product Categories: | | | Mol File: | 532-11-6.mol |  |
| | Anethole trithione Chemical Properties |
| Melting point | 111° | | Boiling point | 353.09°C (rough estimate) | | density | 1.4406 (rough estimate) | | refractive index | 1.5080 (estimate) | | storage temp. | 2-8°C | | solubility | Chloroform[soluble in] | | solubility | soluble in Chloroform | | form | powder to crystal | | color | Orange-colored prisms from butyl acetate | | Odor | very bitter taste | | InChI | InChI=1S/C10H8OS3/c1-11-8-4-2-7(3-5-8)9-6-10(12)14-13-9/h2-6H,1H3 | | InChIKey | KYLIZBIRMBGUOP-UHFFFAOYSA-N | | SMILES | S1C(C2=CC=C(OC)C=C2)=CC(=S)S1 | | CAS DataBase Reference | 532-11-6(CAS DataBase Reference) | | NIST Chemistry Reference | 3H-1,2-Dithiole-3-thione, 5-(4-methoxyphenyl)-(532-11-6) |
| HS Code | 2934.99.3000 | | Toxicity | LD50 orl-mus: 3850 mg/kg NIIRDN 6,25,82 |
| | Anethole trithione Usage And Synthesis |
| Description | Anise trisulfide, also known as bile vita, is a secretory choleretic drug, which can significantly enhance liver glutathione levels, significantly enhance glutamyl cysteine synthase, glutathione reductase and glutathione sulfur Transferase activity, reduce glutathione peroxidase activity, enhance liver cell viability, and increase bile secretion. Without increasing the burden on the liver, it can reduce liver portal pressure, eliminate liver congestion and other symptoms of hepatitis lesions, promote liver cell activation, and contribute to the improvement and recovery of liver function. | | Originator | Sialor,Paladin Labs | | Uses | Anethole trithione is a choleretic drug that can be effective in the treatment of dry mouth, including drug-induced xerostomia. Research suggests that Anethole trithione may exert its therapeutic effects by acting on the alpha-CGRP nerves in the salivary glands, which in turn promotes salivary secretion[1-2]. | | Definition | ChEBI: Anetholtrithion is a member of methoxybenzenes. | | Manufacturing Process | 1 mol anethol (1-methoxy-4-propenyl-benzene) and 3 mol sulfur were heated
in an open vessel to temperature 190°-200°C. H2S was removed at this
temperature. On cooling the reaction mixture was getting solid. The solid
product was recrystallizated from acetone or ethanol to give the orange-red
needles of 5-(4-methoxyphenyl)-3H-1,2-dithiole-3-thione; MP 108.5°C. | | Therapeutic Function | Salivation stimulant, Choleretic, Neuroprotective | | Safety Profile | Poison by intramuscular route.Moderately toxic by ingestion and intraperitoneal routes.Experimental reproductive effects. When heated todecomposition it emits toxic fumes of SOx. | | References | [1] TOSHIAKI NAGANO; Masaharu T. Enhancement of salivary secretion and neuropeptide (substance P, α-calcitonin gene-related peptide) levels in saliva by chronic anethole trithione treatment[J]. Journal of Pharmacy and Pharmacology, 2010. DOI:10.1211/0022357011778098.
[2] GLENERT U. Effects of chronic anethole trithione and amitriptyline treatment on rat parotid gland signalling[J]. European Journal of Pharmacology: Molecular Pharmacology, 1992. DOI:10.1016/0922-4106(92)90081-6.
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| | Anethole trithione Preparation Products And Raw materials |
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