ITSFEEAKGLDRINERMPPRRDAMP manufacturers
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| | ITSFEEAKGLDRINERMPPRRDAMP Basic information |
| Product Name: | ITSFEEAKGLDRINERMPPRRDAMP | | Synonyms: | CN412;ITSFEEAKGLDRINERMPPRRDAMP;H-ILE-THR-SER-PHE-GLU-GLU-ALA-LYS-GLY-LEU-ASP-ARG-ILE-ASN-GLU-ARG-MET-PRO-PRO-ARG-ARG-ASP-ALA-MET-PRO-OH;ILE-THR-SER-PHE-GLU-GLU-ALA-LYS-GLY-LEU-ASP-ARG-ILE-ASN-GLU-ARG-MET-PRO-PRO-ARG-ARG-ASP-ALA-MET-PRO;CALCINEURIN AUTOINHIBITORY FRAGMENT;CALCINEURIN AUTOINHIBITORY PEPTIDE;ILE-THR-SER-PHE-GLU-GLU-ALA-LYS-GLY-LEU-ASP-ARG-ILE-ASN-GLU-ARG-MET-PRO-PRO-ARG-ARG-ASP-ALA-MET-PRO: ITSFEEAKGLDRINERMPPRRDAMP;CalcineurinAutoinhibitoryPeptide,CalcineurinAutoinhibitoryPeptid | | CAS: | 148067-21-4 | | MF: | C124H205N39O39S2 | | MW: | 2930.32 | | EINECS: | | | Product Categories: | Peptide | | Mol File: | 148067-21-4.mol |  |
| | ITSFEEAKGLDRINERMPPRRDAMP Chemical Properties |
| storage temp. | −20°C | | form | Lyophilized solid. | | color | White to off-white | | Water Solubility | Soluble to 1 mg/ml in water |
| | ITSFEEAKGLDRINERMPPRRDAMP Usage And Synthesis |
| Uses | Calcineurin autoinhibitory peptide is a selective inhibitor of Ca2+/calmodulin-dependent protein phosphatase (calcineurin), with an IC50 of ~10 μM. Calcineurin autoinhibitory peptide could protect neurons from excitatory neuronal death[1][2]. | | References | [1] Hashimoto Y, et, al. Identification of an autoinhibitory domain in calcineurin. J Biol Chem. 1990 Feb 5; 265(4): 1924-7. PMID:2153670
[2] Terada H, et, al. Inhibition of excitatory neuronal cell death by cell-permeable calcineurin autoinhibitory peptide. J Neurochem. 2003 Dec; 87(5): 1145-51. DOI:10.1046/j.1471-4159.2003.02098.x |
| | ITSFEEAKGLDRINERMPPRRDAMP Preparation Products And Raw materials |
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