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Sigma-Aldrich
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Product Name:Cyclic adenosine diphosphate-ribose CAS:119340-53-3 Purity:>=90% (HPLC) Package:250μg, 0.5mg Remarks:C7344
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| CADP-RIBOSE Basic information |
Product Name: | CADP-RIBOSE | Synonyms: | CADPR;CADP-RIBOSE;ADP-CYCLO-[N1:1'']-RIBOSE;CADPR SODIUM SALT;cyclicadenosinediphosphateribose(cadpr),sodiumsalt;CYCLIC ADP RIBOSE POTENT INTRACELLULAR;ADP-cyclo[N1:1μμ]-ribose, cADP-ribose, cADPR, Cyclic ADPR;C13050 | CAS: | 119340-53-3 | MF: | C15H21N5O13P2 | MW: | 541.3 | EINECS: | | Product Categories: | | Mol File: | 119340-53-3.mol | ![CADP-RIBOSE Structure](CAS/GIF/119340-53-3.gif) |
| CADP-RIBOSE Chemical Properties |
Boiling point | 934.8±75.0 °C(Predicted) | density | 2.57±0.1 g/cm3(Predicted) | storage temp. | -20°C | solubility | DMSO (Slightly), Methanol (Very Slightly), Water (Slightly) | pka | 0.97±0.70(Predicted) | form | lyophilized powder | color | White to off-white | Stability: | Hygroscopic |
Hazard Codes | Xi | Risk Statements | 36/37/38 | Safety Statements | 26-36 | WGK Germany | 3 |
| CADP-RIBOSE Usage And Synthesis |
Uses | Cyclic adenosine diphosphate-ribose (cADPR) is an intracellular second messenger that mobilizes intracellular Ca2+ release from the sarcoplasmic reticulum through ryanodine receptors. CADPR is also a second messenger for glucose-induced insulin release from endocrine pancreas and for abscisic acid-induced calcium release in plants. | Definition | ChEBI: A cyclic purine nucleotide that is synthesised from NAD+ by ADP-ribosyl cyclase; acts as an agonist at ryanodine receptors. | Biochem/physiol Actions | Mobilizes intracellular Ca2+; regulates Ca2+-induced Ca2+?release specifically blocked by ryanodine; second messenger for glucose-induced insulin release from the endocrine pancreas and for abscisic acid-induced calcium release in plants. |
| CADP-RIBOSE Preparation Products And Raw materials |
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