| Company Name: |
3B Pharmachem (Wuhan) International Co.,Ltd.
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| Tel: |
821-50328103-801 18930552037 |
| Email: |
3bsc@sina.com |
| Products Intro: |
Product Name:TCS 46b;1,3-Dihydro-5-[3-[4-(phenylMethyl)-1-2H-benziMidazol-2-one
CAS:302799-86-6
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g
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| | TCS 46B Basic information |
| Product Name: | TCS 46B | | Synonyms: | TCS 46B;1,3-Dihydro-5-[3-[4-(phenylmethyl)-1-2H-benzimidazol-2-one;2H-Benzimidazol-2-one, 1,3-dihydro-5-[3-[4-(phenylmethyl)-1-piperidinyl]-1-propyn-1-yl]- | | CAS: | 302799-86-6 | | MF: | C22H23N3O | | MW: | 345.44 | | EINECS: | | | Product Categories: | | | Mol File: | 302799-86-6.mol |  |
| | TCS 46B Chemical Properties |
| Boiling point | 440.4±38.0 °C(Predicted) | | density | 1.24±0.1 g/cm3(Predicted) | | storage temp. | Store at RT | | solubility | Soluble to 100 mM in DMSO and to 100 mM in ethanol | | form | Powder | | pka | 11.51±0.30(Predicted) | | color | Off-white to light yellow |
| | TCS 46B Usage And Synthesis |
| Uses | TCS 46b is a subtype-selective NR1A/NR2B NMDA receptor antagonist. | | Biological Activity | Orally active, subtype-selective NR1A/NR2B NMDA receptor antagonist (IC 50 values are 5.3, 35000 and > 100000 nM for NR1A/2B, NR1A/2A and NR1A/2C receptor subtypes respectively). Potentiates the effect of L-DOPA in 6-OHDA-lesioned rats following oral administration. |
| | TCS 46B Preparation Products And Raw materials |
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