| Company Name: |
BOC Sciences
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| Tel: |
1-631-485-4226; 16314854226 |
| Email: |
info@bocsci.com |
| Products Intro: |
Product Name:CAY10397
CAS:78028-01-0
Purity:>=98% Remarks:Reach out to us for more information about custom solutions.
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| Company Name: |
Guangzhou Isun Pharmaceutical Co., Ltd
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| Tel: |
020-39119399 18927568969 |
| Email: |
isunpharm@qq.com |
| Products Intro: |
Product Name:CAY10397
CAS:78028-01-0
Purity:>=98% Package:5MG; 25MG; 100MG; 1G
|
| Company Name: |
BOC Sciences
|
| Tel: |
16314854226 |
| Email: |
info@bocsci.com |
| Products Intro: |
Product Name:CAY10397
CAS:78028-01-0
Purity:98% Package:1G;10G;100G Remarks:Prostaglandins are rapidly inactivated in vivo by the action of 15-hydroxy prostaglandin dehydrogenase (15-hydroxy PGDH). CAY10397 is a selective inhibitor of 15-hydroxy PGDH, significantly suppressin
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| Company Name: |
Hangzhou Synstar pharmaceutical Technology CO.,Ltd
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| Tel: |
0571-85361029 |
| Email: |
synstar518@163.com |
| Products Intro: |
Product Name:5-[[4-(ethoxycarbonyl)phenyl]azo]-2-hydroxy-benzeneacetic acid
CAS:78028-01-0
Purity:0.98 Package:100mg、500mg、1g、5g
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- CAY10397
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- $148.00 / 1mg
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2024-10-24
- CAS:78028-01-0
- Min. Order:
- Purity:
- Supply Ability: 10g
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| | CAY10397 Basic information |
| Product Name: | CAY10397 | | Synonyms: | CAY10397;CK47A;Ph CK 47A;5-[[4-(ETHOXYCARBONYL)PHENYL]AZO]-2-HYDROXY-BENZENEACETIC ACID;5-[[4-(Ethoxycarbonyl)phenyl]azo]-2-hydroxybenzeneacetic acid, CK47A;5-[2-[4-(Ethoxycarbonyl)phenyl]diazenyl]-2-hydroxybenzeneacetic acid;DPHOCQNZARWEHS-UHFFFAOYSA-N;CAY-10397,CAY10397 | | CAS: | 78028-01-0 | | MF: | C17H16N2O5 | | MW: | 328.32 | | EINECS: | | | Product Categories: | | | Mol File: | 78028-01-0.mol |  |
| | CAY10397 Chemical Properties |
| Boiling point | 578.0±50.0 °C(Predicted) | | density | 1.29±0.1 g/cm3(Predicted) | | storage temp. | −20°C | | solubility | 0.1 M Na2CO3: 200 μg/ml; DMF: 35 mg/ml; DMSO: 25 mg/ml; Ethanol: 10 mg/ml | | pka | 4.05±0.10(Predicted) | | form | solid |
| | CAY10397 Usage And Synthesis |
| Uses | Prostaglandins are rapidly inactivated in vivo by the action of 15-hydroxy prostaglandin dehydrogenase (15-hydroxy PGDH). This enzyme oxidizes the 15-hydroxyl group and hydrogenates the 13,14-double bond, producing 13,14-dihydro-15 keto metabolites with greatly reduced biological activity. CAY10397 is a selective inhibitor of 15-hydroxy PGDH with an IC50 of approximately 10 μM. CAY10397 acts to prolong the lifetime and activity of endogenously produced prostaglandins both in cell culture and in vivo.[Cayman Chemical] | | Definition | ChEBI: CAY10397 is a member of the class of azobenzenes that is azobenzene in which one of the phenyl groups is substituted at position 4 by an ethoxycarbonyl group, while the other is substituted by a carboxymethyl group at position 3 and a hydroxy group at position 4. It is a potent and selective inhibitor of 15-hydroxyprostaglandin dehydrogenase (15-hydroxy-PGDH). It has a role as an EC 1.1.1.141 [15-hydroxyprostaglandin dehydrogenase (NAD(+))] inhibitor. It is a dicarboxylic acid monoester, an ethyl ester, a member of azobenzenes and a member of phenols. | | Biological Activity | Potent and selective inhibitor of 15-hydroxyprostaglandin dehydrogenase (15-hydroxy-PGDH). Acts to prolong the lifetime and activity of endogenously produced prostaglandins both in vitro and in vivo. |
| | CAY10397 Preparation Products And Raw materials |
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