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| | Bis[(pinacolato)boryl]Methane Basic information |
| Product Name: | Bis[(pinacolato)boryl]Methane | | Synonyms: | 2,2'-Methylenebis[4,4,5,5-tetraMethyl-1,3,2-dioxaborolane;Bis[(pinacolato)boryl]Methane;Bis[(pinacolato);4,4,5,5-tetramethyl-2-[(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)methyl]-1,3,2-dioxaborolan;Methylenedi(boronic Acid Pinacol Ester);Bis[(pinacolato)boryl]methane >;1,3,2-Dioxaborolane, 2,2'-methylenebis[4,4,5,5-tetramethyl-;Bis(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)Methane | | CAS: | 78782-17-9 | | MF: | C13H26B2O4 | | MW: | 267.97 | | EINECS: | | | Product Categories: | Boron Derivatives;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals | | Mol File: | 78782-17-9.mol | ![Bis[(pinacolato)boryl]Methane Structure](CAS/GIF/78782-17-9.gif) |
| | Bis[(pinacolato)boryl]Methane Chemical Properties |
| Melting point | 51.0 to 55.0 °C | | Boiling point | 272.0±23.0 °C(Predicted) | | density | 0.97±0.1 g/cm3(Predicted) | | Fp | >110℃ | | storage temp. | 2-8°C | | solubility | Chloroform (Slightly), Methanol (Slightly) | | form | Solid | | color | White to Off-White | | InChIKey | MQYZGGWWHUGYDR-UHFFFAOYSA-N | | CAS DataBase Reference | 78782-17-9 |
| WGK Germany | 3 | | HS Code | 2931900090 |
| | Bis[(pinacolato)boryl]Methane Usage And Synthesis |
| Chemical Properties | White to Off-White Low Melting Solid | | Uses | An organoboronate derivative that is an inhibitor of matrix metallo-proteinase (MMP-2). | | Uses | Bis-boronate has been reported by Morken and coworkers to be a key building block in the synthesis of enantioenriched secondary boronate esters, which undergo facile Suzuki-Miyaura coupling with minimal erosion of enantiopurity. | | General Description | We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Greener Chemistry. This product has been enhanced for catalytic efficiency. Click here for more information. |
| | Bis[(pinacolato)boryl]Methane Preparation Products And Raw materials |
| Raw materials | Boronic acid, methylenebis-, tetramethyl ester-->Iodomethylboronic acid, pinacol ester-->1,2-Bis((pinacolato)boryl)ethane-->Diiodomethane-->Dichloromethane-->Dibromomethane-->carbon monoxide-->Pinacol | | Preparation Products | 3,4-Dithia-7H-cyclopenta[a]pentalene-->4,4'-DDM-->tert-Butyl 4-((4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)methylene)piperidine-1-carboxylate-->3-CHLOROPHENYLBORONIC ACID, PINACOL ESTER-->4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)CHLOROBENZENE-->1-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole-->2-cyclopentyl-4,4,5,5-tetraMethyl-1,3,2-dioxaborolane-->Methyl boronic acid pinacol ester-->6-Bromo-2-methylquinoline |
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