Deoxycytidine triphosphate trisodium salt manufacturers
- dCTP-trisodium-salt
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- $0.00 / 100ml
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2023-03-14
- CAS:109909-44-6
- Min. Order: 100ml
- Purity: ≥99%(HPLC)
- Supply Ability: 20000l
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| Deoxycytidine triphosphate trisodium salt Basic information |
Product Name: | Deoxycytidine triphosphate trisodium salt | Synonyms: | 2'-DEOXYCYTIDINE 5'-TRIPHOSPHATE (SODIUM SALT);2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE TRISODIUM SALT;2'-DEOXYCYTIDINE-5'-TRIPHOSPHORIC ACID TRISODIUM SALT;Dctp-Na3;Deoxycytidine-5'-Triphosphoric Acid Trisodium Sal;dCTP,3Na;CYTIDINE 5''-(TETRAHYDROGEN TRIPHOSPHATE), 2''-DEOXY-, TRISODIUM SALT;((2R,3S,5R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-3-hydroxytetrahydrofuran-2-yl)methyltriphosphoric acid, trisodium salt | CAS: | 109909-44-6 | MF: | C9H17N3NaO13P3 | MW: | 491.15 | EINECS: | | Product Categories: | PCR;dNTP | Mol File: | 109909-44-6.mol | |
| Deoxycytidine triphosphate trisodium salt Chemical Properties |
storage temp. | -20°C | solubility | Water: 10 mg/ml | form | A crystalline solid | color | Colorless to light yellow | Water Solubility | Water: 10 mg/ml | InChIKey | WBIPTAOOMJEGQO-JXXKLNQHNA-K | SMILES | N1(C=CC(N)=NC1=O)[C@H]1C[C@H](O)[C@@H](COP([O-])(=O)OP([O-])(=O)OP([O-])(=O)O)O1.[Na+].[Na+].[Na+] |&1:8,10,12,r| | CAS DataBase Reference | 109909-44-6(CAS DataBase Reference) |
| Deoxycytidine triphosphate trisodium salt Usage And Synthesis |
Description | Deoxycytidine triphosphate trisodium salt (dCTP trisodium salt or 2′-Deoxycytidine-5′-triphosphate trisodium salt) is a nucleoside triphosphate that can be used for DNA synthesis. Deoxycytidine triphosphate trisodium salt has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing.
| Uses |
Deoxycytidine triphosphate trisodium salt (2′-Deoxycytidine-5′-triphosphate trisodium salt) is an activator that has been shown to exhibit anticancer and antiviral activities. It is a novel nucleoside phosphoramidite that is used in the synthesis of DNA, RNA, and other nucleic acids. 2′-Deoxycytidine-5′-triphosphate trisodium salt has been modified by substituting the oxygen atom for a sulfur atom at the 5' position of the sugar moiety. This change makes it resistant to degradation by ribonucleases. 2′-Deoxycytidine-5′-triphosphate trisodium salt has also been shown to act as an inhibitor of human telomerase activity.
| in vitro |
Assays of thirteen cell lines, derived from mouse lymphomas, myelomas, myeloid tumors, and a mastocytoma, for sensitivity to growth inhibition by 1-β-D-arabinofuranosylcytosine (ara-C) revealed a spectrum between the most and least sensitive which differed 100-fold from each other. An inverse correlation between sensitivity and cellular Deoxycytidine triphosphate (2′-Deoxycytidine-5′-triphosphate, dCTP) content is found, and this suggested that sensitivity of cells might be increased if the dCTP content was lowered during cell exposure to ara-C. Deoxycytidine triphosphate trisodium salt is a phosphoethanolamine cytidylyltransferase substrate.
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| Deoxycytidine triphosphate trisodium salt Preparation Products And Raw materials |
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