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| | GW791343 HCl Basic information |
| Product Name: | GW791343 HCl | | Synonyms: | GW791343 (trihydrochloride);2-(3,4-difluorophenylamino)-N-(2-methyl-5-(piperazin-1-ylmethyl)phenyl)acetamide trihydrochloride;GW791343 3HCl;GW 791343 TRIHYDROCHLORIDE; GW-791343 TRIHYDROCHLORIDE;;GW791343 HCl USP/EP/BP;2-((3,4-difluorophenyl)amino)-N-(2-methyl-5-(piperazin-1-ylmethyl)phenyl)acetamide hydrogen chloride | | CAS: | 309712-55-8 | | MF: | C20H27Cl3F2N4O | | MW: | 483.8103864 | | EINECS: | | | Product Categories: | Inhibitors | | Mol File: | 309712-55-8.mol |  |
| | GW791343 HCl Chemical Properties |
| storage temp. | Store at -20°C | | solubility | Soluble to 100 mM in water and to 100 mM in DMSO | | form | Powder | | CAS DataBase Reference | 309712-55-8 |
| | GW791343 HCl Usage And Synthesis |
| Uses | GW 791343 Trihydrochloride is a P2X7 receptor antagonist that acts as an allosteric inhibitor, exhibiting negative allosteric effects at the human P2X7 receptor and positive allosteric effects at the rat P2X7 receptor. P2X7 receptor is responsible for the presence of inflammatory cells, regulated by extracellular ATP. |
| | GW791343 HCl Preparation Products And Raw materials |
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