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| | 3'-bromo-2'-methylacetophenone Basic information |
| Product Name: | 3'-bromo-2'-methylacetophenone | | Synonyms: | 3'-broMo-2'-Methylacetophenone;1-(3-Bromo-2-methylphenyl)ethanone;1-(3-bromo-2-methylphenyl)ethan-1-one;Fluralaner-006;Ethanone, 1-(3-bromo-2-methylphenyl)-;1-(3-Bromo-2-Methylphenyl)Ethanone(WXC02293);Fluralaner Impurity 32;3'-broMo-2'-Methylacetophenone | | CAS: | 52779-76-7 | | MF: | C9H9BrO | | MW: | 213.07 | | EINECS: | | | Product Categories: | | | Mol File: | 52779-76-7.mol |  |
| | 3'-bromo-2'-methylacetophenone Chemical Properties |
| Boiling point | 272.7±28.0 °C(Predicted) | | density | 1.388±0.06 g/cm3(Predicted) | | storage temp. | Sealed in dry,Room Temperature | | InChI | InChI=1S/C9H9BrO/c1-6-8(7(2)11)4-3-5-9(6)10/h3-5H,1-2H3 | | InChIKey | LBNWYNIGDUWAOQ-UHFFFAOYSA-N | | SMILES | C(=O)(C1=CC=CC(Br)=C1C)C |
| | 3'-bromo-2'-methylacetophenone Usage And Synthesis |
| Synthesis |
To a stirred and refluxing Grignard-complex, previously prepared starting from 7.3 parts of magnesium, 52.6 parts of methyl iodide in 160 parts of ether, is added dropwise a solution of 19.6 parts of 3'-bromo-2'-methylbenzonitrile in 40 parts of ether. Upon completion, stirring at reflux is continued for 20 hours. The reaction mixture is cooled to 0 C and poured onto 500 parts of ice water while stirring vigorously. The ethereal phase is separated, dried and evaporated. The residue is boiled in 60 parts of a 6N hydrochloric acid solution for 10 minutes. The separated oil is extracted with ether. The extract is washed with water, dried and evaporated. The residue is distilled, yielding 3'-bromo-2'-methylacetophenone.
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| | 3'-bromo-2'-methylacetophenone Preparation Products And Raw materials |
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