| Company Name: |
Biomatrik (Jiaxing) Inc.
|
| Tel: |
573-573-82623377 18967387295 |
| Email: |
sales@biomatrik.cn |
| Products Intro: |
Product Name:mPEG11-CH2CH2COONHS
CAS:2207596-93-6
Purity:97% Package:1g;5g;500g
|
| Company Name: |
Chengdu Pukang Biotechnology Co., Ltd
|
| Tel: |
028-82550498 19102685862 |
| Email: |
sales@pu-kang.com |
| Products Intro: |
Product Name:m-dPEG12-NHS ester
CAS:2207596-93-6
Purity:95%,HPLC Package:10g/;50g/;500g/
|
MPEG11-CH2CH2COONHS manufacturers
- m-PEG12-NHS ester
-
- $0.00 / 1g
-
2024-03-27
- CAS:2207596-93-6
- Min. Order: 1g
- Purity: >95.00%
- Supply Ability: 1g
|
| | MPEG11-CH2CH2COONHS Basic information |
| Product Name: | MPEG11-CH2CH2COONHS | | Synonyms: | MPEG11-CH2CH2COONHS;4,7,10,13,16,19,22,25,28,31,34,37-Dodecaoxaoctatriacontanoic acid, 2,5-dioxo-1-pyrrolidinyl ester;mPEG11-CH2CH2COONHS/4,7,10,13,16,19,22,25,28,31,34,37-Dodecaoxaoctatriacontanoic acid, 2,5-dioxo-1-pyrrolidinyl ester | | CAS: | 2207596-93-6 | | MF: | C30H55NO16 | | MW: | 685.75 | | EINECS: | | | Product Categories: | | | Mol File: | 2207596-93-6.mol |  |
| | MPEG11-CH2CH2COONHS Chemical Properties |
| Boiling point | 684.3±65.0 °C(Predicted) | | density | 1.19±0.1 g/cm3(Predicted) | | form | Liquid | | color | Colorless to light yellow | | InChIKey | ZMXRHHJWXLKMTL-UHFFFAOYSA-N | | SMILES | C(ON1C(=O)CCC1=O)(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC |
| | MPEG11-CH2CH2COONHS Usage And Synthesis |
| Biological Activity | m-PEG12-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. | | References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
| | MPEG11-CH2CH2COONHS Preparation Products And Raw materials |
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