|
|
| | Securinol A Basic information |
| Product Name: | Securinol A | | Synonyms: | Securinol A;7H-5,10b-Ethano-2H-furo[2,3-a]quinolizin-2-one, 4,5,8,9,10,10a-hexahydro-12-hydroxy-, (5S,10aR,10bR,12R)-;Securinol | | CAS: | 5008-48-0 | | MF: | C13H17NO3 | | MW: | 235.28 | | EINECS: | | | Product Categories: | | | Mol File: | 5008-48-0.mol |  |
| | Securinol A Chemical Properties |
| Melting point | 135-136℃ | | Boiling point | 491.8±45.0 °C(Predicted) | | density | 1.37±0.1 g/cm3(Predicted) | | pka | 14.31±0.20(Predicted) |
| | Securinol A Usage And Synthesis |
| Description | One of three closely related alkaloid isolated from Securinega suffructicosa, the base has [α]17D + 58.2° (c 0.14, CHC13) or + 50° (dioxan). It yields a crystalline picrate, m.p. l86-7°C (dec.), and a 3: 5-dinitrobenzoate, m.p. 198-9°C;[α]17D + 55.3° (c 0.10, CHC13). On hydrogenation with Pt02 in AcOH it gives the dihydro derivative, forming a hydrochloride, m.p. 241- 2°C. When treated with methylsulphonyl chloride in pyridine, the base furnishes viroallosecurinine, m.p. 133- 4°C; [α]D + 1200° (c 0.01, EtOH). | | References | Horii et al., Chern. Pharrn. Bull., 13, 1307 (1965) |
| | Securinol A Preparation Products And Raw materials |
|