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| | Imidazole-2-carboxaldehyde Basic information |
| | Imidazole-2-carboxaldehyde Chemical Properties |
| Melting point | 209 °C (dec.) (lit.) | | Boiling point | 296.5±23.0 °C(Predicted) | | density | 1.322±0.06 g/cm3(Predicted) | | storage temp. | Keep in dark place,Inert atmosphere,Room temperature | | solubility | DMSO (Sparingly), Methanol (Slightly, Sonicated) | | form | Solid | | pka | 11.48±0.10(Predicted) | | color | Light Brown to Brown | | Water Solubility | Soluble in water. | | Sensitive | Air Sensitive | | BRN | 4371302 | | InChI | InChI=1S/C4H4N2O/c7-3-4-5-1-2-6-4/h1-3H,(H,5,6) | | InChIKey | XYHKNCXZYYTLRG-UHFFFAOYSA-N | | SMILES | C1(C=O)NC=CN=1 | | CAS DataBase Reference | 10111-08-7(CAS DataBase Reference) | | NIST Chemistry Reference | 1H-imidazole-2-carboxaldehyde(10111-08-7) |
| | Imidazole-2-carboxaldehyde Usage And Synthesis |
| Chemical Properties | White to light brown solid | | Uses | 1H-Imidazole-2-carboxaldehyde is a novel PTP1b inhibitor with potential application to treat type 2 diabetes. | | Uses | Used in a study of the imidazole-directed allylation of aldimines.1 | | Uses | Imidazole-2-carboxaldehyde is a novel protein tyrosine phosphatase 1B (PTP1B) inhibitor with an important application to treat type-2 diabetes. It is used in the preparation of tridentate Schiff-base carboxylate-containing ligands by undergoing condensation reaction with amino acids beta-alanine and 2-aminobenzoic acid. It is also involved in the study of the imidazole-directed allylation of aldimines. | | Synthesis Reference(s) | Organic Syntheses, Coll. Vol. 7, p. 287, 1990
The Journal of Organic Chemistry, 60, p. 1090, 1995 DOI: 10.1021/jo00109a052 |
| | Imidazole-2-carboxaldehyde Preparation Products And Raw materials |
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