|
| Imidazole-2-carboxaldehyde Basic information |
| Imidazole-2-carboxaldehyde Chemical Properties |
Melting point | 209 °C (dec.) (lit.) | Boiling point | 296.5±23.0 °C(Predicted) | density | 1.322±0.06 g/cm3(Predicted) | storage temp. | Keep in dark place,Inert atmosphere,Room temperature | solubility | DMSO (Sparingly), Methanol (Slightly, Sonicated) | form | Solid | pka | 11.48±0.10(Predicted) | color | Light Brown to Brown | Water Solubility | Soluble in water. | Sensitive | Air Sensitive | BRN | 4371302 | InChIKey | XYHKNCXZYYTLRG-UHFFFAOYSA-N | CAS DataBase Reference | 10111-08-7(CAS DataBase Reference) | NIST Chemistry Reference | 1H-imidazole-2-carboxaldehyde(10111-08-7) |
| Imidazole-2-carboxaldehyde Usage And Synthesis |
Chemical Properties | White to light brown solid | Uses | 1H-Imidazole-2-carboxaldehyde is a novel PTP1b inhibitor with potential application to treat type 2 diabetes. | Uses | Used in a study of the imidazole-directed allylation of aldimines.1 | Uses | Imidazole-2-carboxaldehyde is a novel protein tyrosine phosphatase 1B (PTP1B) inhibitor with an important application to treat type-2 diabetes. It is used in the preparation of tridentate Schiff-base carboxylate-containing ligands by undergoing condensation reaction with amino acids beta-alanine and 2-aminobenzoic acid. It is also involved in the study of the imidazole-directed allylation of aldimines. | Synthesis Reference(s) | Organic Syntheses, Coll. Vol. 7, p. 287, 1990 The Journal of Organic Chemistry, 60, p. 1090, 1995 DOI: 10.1021/jo00109a052 |
| Imidazole-2-carboxaldehyde Preparation Products And Raw materials |
|