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| 1H-Benz[de]isoquinolin-1-one,2,4,5,6-tetrahydro-2-[(3S)-1-oxido-1-azabicyclo[2.2.2]oct-3-yl]- Basic information |
Product Name: | 1H-Benz[de]isoquinolin-1-one,2,4,5,6-tetrahydro-2-[(3S)-1-oxido-1-azabicyclo[2.2.2]oct-3-yl]- | Synonyms: | Palonosetron Impurity 2;Palonosetron Related Compound B ((3S)-3-(1-Oxo-5,6-dihydro-1H-benzo[de]isoquinolin-2(4H)-yl)quinucl (1492233);Dehydro N-Oxide Palonosetron;(S)-3-(1-oxo-5,6-dihydro-1H-benzo[de]isoquinolin-2(4H)-yl)quinuclidine 1-oxide HCl;Palonosetron Related Compound B (Palonosetron-3-ene N-Oxide);Dehydro palonosetron N-oxide;Palonosetron USP Related Compound B HCl;(S)-3-(1-oxo-5,6-dihydro-1H-benzo[de]isoquinolin-2(4H)-yl)quinuclidine1-oxide | CAS: | 1021456-82-5 | MF: | C19H22N2O2 | MW: | 310.39 | EINECS: | | Product Categories: | | Mol File: | 1021456-82-5.mol | |
| 1H-Benz[de]isoquinolin-1-one,2,4,5,6-tetrahydro-2-[(3S)-1-oxido-1-azabicyclo[2.2.2]oct-3-yl]- Chemical Properties |
solubility | Methanol (Slightly), Water (Slightly) | form | Solid | pka | 4.72±0.40(Predicted) | color | Off-White to Pale Yellow |
| 1H-Benz[de]isoquinolin-1-one,2,4,5,6-tetrahydro-2-[(3S)-1-oxido-1-azabicyclo[2.2.2]oct-3-yl]- Usage And Synthesis |
Uses | Palonosetron-3-ene N-Oxide is an impurity of Palonosetron (P165800), a serotonin 5-HT3 receptor antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Antiemetic. |
| 1H-Benz[de]isoquinolin-1-one,2,4,5,6-tetrahydro-2-[(3S)-1-oxido-1-azabicyclo[2.2.2]oct-3-yl]- Preparation Products And Raw materials |
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