| Company Name: |
Shanghai Changyan Chem & Tech Co., Ltd.
|
| Tel: |
021-021-20242659 18930833303 |
| Email: |
order@changyanchem.com |
| Products Intro: |
Product Name:methyl (R)-4-(2-chloro-4-fluorophenyl)-2-(3,5-difluoropyridin-2-yl)-6-methyl-1,4-dihydropyrimidine-5-carboxylate
CAS:298708-81-3
Purity:95% HPLC Package:5KG;1KG;500G;100G;50G
|
|
| | Bay 41-4109 Basic information |
| Product Name: | Bay 41-4109 | | Synonyms: | Bay 41-4109;methyl (R)-4-(2-chloro-4-fluorophenyl)-2-(3,5-difluoropyridin-2-yl)-6-methyl-1,4-dihydropyrimidine-5-carboxylate;BAY41-4109; BAY-41-4109; BAYER 41-4109;Bayer 41-4109;5-Pyrimidinecarboxylic acid, 4-(2-chloro-4-fluorophenyl)-2-(3,5-difluoro-2-pyridinyl)-1,4-dihydro-6-methyl-, methyl ester, (4R)-;BAY-41-4109 (R-isomer);Bay 41 4109,Bay 414109 | | CAS: | 298708-81-3 | | MF: | C18H13ClF3N3O2 | | MW: | 395.76 | | EINECS: | | | Product Categories: | | | Mol File: | 298708-81-3.mol |  |
| | Bay 41-4109 Chemical Properties |
| Boiling point | 475.3±45.0 °C(Predicted) | | density | 1.46±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMSO : 100 mg/mL (252.68 mM);Water : < 0.1 mg/mL (insoluble) | | pka | 5.43±0.60(Predicted) | | form | Solid | | color | Light yellow to yellow |
| | Bay 41-4109 Usage And Synthesis |
| Biological Activity | BAY 41-4109 is a potent inhibitor of human hepatitis B virus (HBV) with IC50 value of 53 nM. | | in vivo | BAY 41-4109 reduces viral DNA in the liver and in the plasma dose-dependently with efficacy comparable to 3TC. BAY 41 -4109 reduces hepatitis B virus core antigen (HBcAg) in livers of HBV-transgenic mice. | | target | |
| | Bay 41-4109 Preparation Products And Raw materials |
|