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1-(4-(Aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine dihydrochloride

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1-(4-(Aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine dihydrochloride Suppliers list
Company Name: BOC Sciences
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Products Intro: Product Name:TLR7/8 agonist 1 dihydrochloride
CAS:1620278-72-9
Package:100mg Remarks:BOC Sciences also provides custom synthesis services for TLR7/8 agonist 1 dihydrochloride.
Company Name: Career Henan Chemica Co
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Products Intro: Product Name:1-(4-(Aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine dihydrochloride
CAS:1620278-72-9
Purity:98% 125 email:hanne@coreychem.com Package:1g;1USD
Company Name: HANGZHOU CLAP TECHNOLOGY CO.,LTD
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Products Intro: Product Name:1-(4-(Aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine dihydrochloride
CAS:1620278-72-9
Purity:99% Package:10kg 25kg 200 kilograms per barrel Remarks:good
Company Name: Henan Alfa Chemical Co., Ltd
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Products Intro: CAS:1620278-72-9
Purity:97%+ Package:25g; 100g; 500g; 1kg; 25kg;bulk package
Company Name: Nantong HI-FUTURE Biology Co., Ltd.
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Products Intro: Product Name:TLR7/8 agonist 1 dihydrochloride
CAS:1620278-72-9
Purity:98% HPLC Package:100mg，500mg，1g，5g，10g
1-(4-(Aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine dihydrochloride Basic information
Product Name:1-(4-(Aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine dihydrochloride
Synonyms:1-(4-(Aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine dihydrochloride;TLR7/8 agonist 1 (dihydrochloride);TLR7/8 agonist-5d;TLR7/8 Agonist 1 (hydrochloride);8 agonist 1 dihydrochloride;TLR7/8 Agonist 5d (hydrochloride);Toll-like Receptor (TLR),TLR7/8 agonist 1,TLR7/8 agonist 1 dihydrochloride,TLR-7/8 agonist 1 dihydrochloride,Inhibitor,inhibit;TLR7/8 agonist 1 2HCl
CAS:1620278-72-9
MF:C22H26ClN5
MW:395.94
EINECS:
Product Categories:
Mol File:1620278-72-9.mol
1-(4-(Aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine dihydrochloride Structure
1-(4-(Aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine dihydrochloride Chemical Properties
storage temp. Store at -20°C
solubility DMSO:83.33(Max Conc. mg/mL);192.72(Max Conc. mM)
form A solid
color Off-white to light yellow
Safety Information
MSDS Information
1-(4-(Aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine dihydrochloride Usage And Synthesis
Biological ActivityTLR7/8 agonist 1 dihydrochloride is a dual agonist of the toll-like receptor TLR7/TLR8.
in vitro

TLR7/8 agonist 1 (Compound 5d) shows prominent immunostimulatory activities. TLR7/8 agonist 1 serves as a convenient precursor for the covalent attachment of fluorophores without significant loss of activity.It retains TLR7- agonistic activity with an EC 50 of 20 nM. TLR7/8 agonist 1 (Compound 1) shows substantially different agonistic potencies in human TLR7 (50 nM) and TLR8 (55 nM) primary screens.

target

TLR7/TLR8

1-(4-(Aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine dihydrochloride Preparation Products And Raw materials
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