TLR7/8激动剂1二盐酸盐
| 中文名称 | TLR7/8激动剂1二盐酸盐 |
|---|---|
| 中文同义词 | 1-(4-(氨基甲基)苄基)-2-丁基-1H-咪唑并[4,5-C]喹啉-4-胺二盐酸盐;二盐酸TLR7/8 AGONIST 1;TLR7/8激动剂1二盐酸盐 |
| 英文名称 | 1-(4-(Aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine dihydrochloride |
| 英文同义词 | 1-(4-(Aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine dihydrochloride;TLR7/8 agonist 1 (dihydrochloride);TLR7/8 agonist-5d;TLR7/8 Agonist 1 (hydrochloride);8 agonist 1 dihydrochloride;TLR7/8 Agonist 5d (hydrochloride);Toll-like Receptor (TLR),TLR7/8 agonist 1,TLR7/8 agonist 1 dihydrochloride,TLR-7/8 agonist 1 dihydrochloride,Inhibitor,inhibit;TLR7/8 agonist 1 2HCl |
| CAS号 | 1620278-72-9 |
| 分子式 | C22H26ClN5 |
| 分子量 | 395.94 |
| EINECS号 | |
| 相关类别 | 合成材料中间体 |
| Mol文件 | 1620278-72-9.mol |
| 结构式 |  |
TLR7/8激动剂1二盐酸盐 性质
| 储存条件 | Store at -20°C |
|---|---|
| 溶解度 | DMSO：83.33（最大浓度 mg/mL）；192.72（最大浓度 mM） |
| 形态 | 固体 |
| 颜色 | 米白色至浅黄色 |
TLR7/8 agonist 1 dihydrochloride 是一种 toll 样受体 TLR7/TLR8 的双重激动剂。
TLR7/TLR8
TLR7/8 agonist 1 (Compound 5d) shows prominent immunostimulatory activities. TLR7/8 agonist 1 serves as a convenient precursor for the covalent attachment of fluorophores without significant loss of activity. TLR7/8 agonist 1 retains TLR7-agonistic activity with an EC 50 of 20 nM. TLR7/8 agonist 1 (Compound 1) shows substantially different agonistic potencies in human TLR7 (50 nM) and TLR8 (55 nM) primary screens.
安全信息
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2024/04/30 | HY-103698A | TLR7/8 agonist 1 dihydrochloride | 1 mg | 1363元 | |
| 2024/04/30 | HY-103698A | 1620278-72-9 TLR7/8 agonist 1 dihydrochloride | 1620278-72-9 | 10mM * 1mLin DMSO | 3300元 |