FARNESYLPYROPHOSPHATE

FARNESYLPYROPHOSPHATE Suppliers list
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Products Intro: Product Name:Farnesyl diphosphate-TA
CAS:13058-04-3
Package:160EUR/0.5mg Remarks:LA 68-1520-35
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Products Intro: Product Name:FARNESYLPYROPHOSPHATE
CAS:13058-04-3
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g
Company Name: Shanghai Macklin Biochemical Co.,Ltd.  
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Products Intro: Product Name:Farnesyl pyrophosphate ammonium salt methanol:ammonia solution
CAS:13058-04-3
Purity:95%, 1 mg/mL in methanol:ammonia solution Package:200μg
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Products Intro: Product Name:Farnesyl pyrophosphate ammonium salt
CAS:13058-04-3
Purity:methanol:ammonia solution, >=95% (TLC) Package:1VL Remarks:F6892-1VL
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Products Intro: Product Name:Farnesylpyrophosphate
CAS:13058-04-3
Purity:methanol:ammonia solution, >=95%(TLC) Package:200ug Remarks:S22674
FARNESYLPYROPHOSPHATE Basic information
Product Name:FARNESYLPYROPHOSPHATE
Synonyms:FARNESYLPYROPHOSPHATE TRIAMMONIUM SALT SOLUTION;FPP, 3,7,11-Trimethyl-2,6,10-dodecatrien-1-yl pyrophosphate ammonium salt;(2E,6E)-3,7,11-Trimethyldodeca-2,6,10-triene-1-ol diphosphoric acid;(E,E)-Farnesyl pyrophosphate;3,7,11-TRIMETHYL-2,6,10-DODECATRIEN-1-OL PYROPHOSPHATE;3,7,11-TRIMETHYL-2,6,10-DODECATRIEN-1-OL PYROPHOSPHATE 3NH3;3,7,11-TRIMETHYL-2,6,10-DODECATRIEN-1-OL PYROPHOSPHATE AMMONIUM SALT;FARNESYLPYROPHOSPHATE TRIAMMONIUM SALT
CAS:13058-04-3
MF:C15H28O7P2
MW:382.33
EINECS:
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Mol File:13058-04-3.mol
FARNESYLPYROPHOSPHATE Structure
FARNESYLPYROPHOSPHATE Chemical Properties
Melting point >107°C (dec.)
Boiling point 533.8±60.0 °C(Predicted)
density 1.233±0.06 g/cm3(Predicted)
Fp 11 °C
storage temp. -20°C
solubility Methanol (Slightly, Sonicated), Water (Slightly)
form methanol:ammonia solution
pka1.07±0.50(Predicted)
color White to Brown
Stability:Hygroscopic, Light Sensitive, Temperature Sensitive
Safety Information
Hazard Codes F,T
Risk Statements 11-23/24/25-39/23/24/25
Safety Statements 7-16-36/37-45
RIDADR UN 1230 3/PG 2
WGK Germany 1
MSDS Information
ProviderLanguage
SigmaAldrich English
FARNESYLPYROPHOSPHATE Usage And Synthesis
UsesFarnesyl pyrophosphate ammonium salt has been used:
  • as a prenylation agonist in human osteogenic sarcoma cells in collagen-based cell invasion assays
  • in the prenylation of the hepatocyte growth factor (HGF) in human umbilical vein endothelial cells (HUVECs)
  • as a substrate in prenyltransferases assay in diatom Haslea ostrearia

DefinitionChEBI: 2-trans,6-trans-farnesyl diphosphate is the trans,trans-stereoisomer of farnesyl diphosphate. It has a role as an Escherichia coli metabolite and a mouse metabolite. It is a conjugate acid of a 2-trans,6-trans-farnesyl diphosphate(3-).
General DescriptionFarnesyl pyrophosphate is a 15-carbon isoprenoid synthesized from geranyl pyrophosphate (GPP) by the action of enzyme farnesyl pyrophosphate synthase (FPPS).
Biochem/physiol ActionsFarnesyl pyrophosphate (FPP) is the precursor for the biosynthesis of cholesterol, ubiquinone and dolicol. It is part of the intracellular mevalonate pathway. FPP is essential for cell survival and is used for prenylation of several low molecular mass G proteins, including Ras. Inhibition of prenylation results in loss of oncogenic potential of Ras proteins. Inhibition of prenylation may serve as therapeutic potential for management of synaptic plasticity and Alzheimer′s disease.
Purification MethodsPurify the pyrophosphate by chromatography on Whatman No3 MM paper in a system of isopropanol-isobutanol/ammonia/water (40:20:1:30) (v/v). Store it as the Li or NH4 salt at 0o. See geranylgeranyl pyrophosphate below.
FARNESYLPYROPHOSPHATE Preparation Products And Raw materials
Tag:FARNESYLPYROPHOSPHATE(13058-04-3) Related Product Information
farnesylpyrophosphate cyclase FARNESYLPYROPHOSPHATE OCTAPRENYL PYROPHOSPHATE TRIAMMONIUM SALT OCTAPRENYL PYROPHOSPHATE TRIAMMONIUM SALT, [1-3H] Geranylgeranyl pyrophosphate TRANS-GERANYLGERANYL-PYROPHOSPHATE, [1-3H] TRIAMMONIUM SALT FPP [1-3H] ALL TRANS-3,7,11,15-TETRAMETHYL-2,6,10,14-HEXADECATETRAENYL TRIPHOSPHATE AMMONIUM SALT 3,7,11-TRIMETHYL-2,6,10-DODECATRIEN-1-YL TRIPHOSPHATE AMMONIUM SALT TRANS, TRANS FARNESYL TRIPHOSPHATE, TRIAMMONIUM SALT, [1,2-14C] FARNESYL PYROPHOSPHATE-[1-3H(N)] TRIAMMONIUM SALT ALL TRANS GERANYL GERANYL PYROPHOSPHATE, [1-3H], TRIAMMONIUM SALT HEXAPRENYL PYROPHOSPHATE TRIAMMONIUM SALT TRANS, TRANS FARNESYL TRIPHOSPHATE, TETRAAMMONIUM SALT, [1-3H]

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