N-(4-AMINOBUTYL)-5-CHLORO-2-NAPHTHALENESULFONAMIDE HYDROCHLORIDE

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Company Name:	TargetMol Chemicals Inc.
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Products Intro:	Product Name:W-13 hydrochloride CAS:88519-57-7 Purity:98.51% Package:1mg;30USD\|5mg;64USD\|10mg;109USD Remarks:REAGENT;FOR LABORATORY USE ONLY

Company Name:	Dayang Chem (Hangzhou) Co.,Ltd.
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Products Intro:	Product Name:N-(4-Aminobutyl)-5-Chloronaphthalene-2-Sulfonamide Hydrochloride CAS:88519-57-7 Purity:0.95&0.99 Package:0.1KG;1KG;1000KG Remarks:High quality

Company Name:	Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd
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Products Intro:	Product Name:N-(4-AMINOBUTYL)-5-CHLORO-2-NAPHTHALENESULFONAMIDE HYDROCHLORIDE CAS:88519-57-7 Purity:N-(4-AMINOBUTYL)-5-CHLORO-2-NAPHTHALENESULFONAMIDE HYDROCHLO Package:1g;5g;10g Remarks:98% HPLC

Company Name:	Jilin Chinese Academy of Sciences-yanshen Technology
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Products Intro:	Product Name:N-(4-Aminobutyl)-5-chloronaphthalene-2-sulfonamide hydrochloride CAS:88519-57-7 Purity:95%+ Package:1g;5g;10g;25g;50g;100g; Remarks:accept Custom Synthesis Services, support large packing

Company Name:	Aladdin Scientific
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Products Intro:	Product Name:W-13 hydrochloride CAS:88519-57-7 Purity:95% Package:$74.9/5mg;$153.9/10mg;$256.9/25mg;$616.9/50mg;Bulk package Remarks:95%

N-(4-AMINOBUTYL)-5-CHLORO-2-NAPHTHALENESULFONAMIDE HYDROCHLORIDE manufacturers

N-(4-AMINOBUTYL)-5-CHLORO-2-NAPHTHALENESULFONAMIDE HYDROCHLORIDE Basic information

Product Name:	N-(4-AMINOBUTYL)-5-CHLORO-2-NAPHTHALENESULFONAMIDE HYDROCHLORIDE
Synonyms:	N-(4-AMINOBUTYL)-5-CHLORO-2-NAPHTHALENESULFONAMIDE HYDROCHLORIDE;N-(4-AMINOBUTYL)-5-CHLORO-2-NAPHTHALENE SULPHONAMIDE, HYDROCHLORIDE;OMEGA-13 HYDROCHLORIDE;W-13;W-13 HYDROCHLORIDE;N-(4-Aminohexyl)-5-chloro-2-naphthalenesulfonamide hydrochloride;(+)-5-Hydroxy-8-[5-(5-hydroxy-7-methoxy-4-oxo-4H-1-benzopyran-2-yl)-2-methoxyphenyl]-7-methoxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one;N-(4-Aminobutyl)-5-chloronaphthalene-2-sulphonamide hydrochloride
CAS:	88519-57-7
MF:	C14H18Cl2N2O2S
MW:	349.28
EINECS:
Product Categories:	All Inhibitors;Inhibitors;Protein Kinase Inhibitors and Activators;Calcium signaling;Amines;Aromatics;Sulfur & Selenium Compounds
Mol File:	88519-57-7.mol

N-(4-AMINOBUTYL)-5-CHLORO-2-NAPHTHALENESULFONAMIDE HYDROCHLORIDE Chemical Properties

Melting point	241-243°C
storage temp.	room temp
solubility	H₂O: Stock solutions of 5 mM are recommended. These stocks should be stable for up to 6 months when stored at 4°C.soluble
form	powder
color	white
Water Solubility	water: 35mg/mL
CAS DataBase Reference	88519-57-7(CAS DataBase Reference)

Safety Information

MSDS Information

Provider	Language
SigmaAldrich	English

N-(4-AMINOBUTYL)-5-CHLORO-2-NAPHTHALENESULFONAMIDE HYDROCHLORIDE Usage And Synthesis

Description	W-13 is a naphthalenesulfonamide derivative that acts as a potent antagonist of calmodulin (IC₅₀ = 22 μM) and is widely used to investigate Ca²⁺/calmodulin-regulated enzyme activities.
Chemical Properties	Beige Solid
Uses	Calmodulin antagonist that binds to calmodulin and inhibits calcium-ion-calmodulin- regulated activities, including phosphodiesterase activation and myosin light chain kinase127, it is widely used to investigate Ca2+/calmodulin-regulated enzyme activities.
Uses	W-13 is a naphthalenesulfonamide derivative that acts as a potent antagonist of calmodulin (IC50 = 22 μM) and is widely used to investigate Ca2+/calmodulin-regulated enzyme activities.
Definition	ChEBI: N-(4-aminobutyl)-5-chloronaphthalene-2-sulfonamide hydrochloride is a hydrochloride salt prepared from equimolar amounts of N-(4-aminobutyl)-5-chloronaphthalene-2-sulfonamide and hydrogen chloride. It contains a N-(4-aminobutyl)-5-chloronaphthalene-2-sulfonamide(1+).
Biological Activity	Calmodulin antagonist (inhibits calmodulin activated PDE activity with an IC 50 of 68 μ M). Inhibits growth of tamoxifen-resistant breast cancer cells.
Biochem/physiol Actions	W-13 has also been shown to inhibit the transcytosis of IgA, recycling of transferrin and overall alter the endocytic pathway in Madin-Darby canine kidney cells.
storage	Store at RT

N-(4-AMINOBUTYL)-5-CHLORO-2-NAPHTHALENESULFONAMIDE HYDROCHLORIDE Preparation Products And Raw materials

Tag:N-(4-AMINOBUTYL)-5-CHLORO-2-NAPHTHALENESULFONAMIDE HYDROCHLORIDE(88519-57-7) Related Product Information

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