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Clobetasone butyrate

Clobetasone butyrate Suppliers list
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CAS:25122-57-0
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Clobetasone butyrate manufacturers

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  • CAS:25122-57-0
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  • 2023-09-06
  • CAS:25122-57-0
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Clobetasone butyrate Basic information
Product Name:Clobetasone butyrate
Synonyms:(16-beta)-);11,20-trione,21-chloro-9-fluoro-17-hydroxy-16-beta-methyl-pregna-4-diene-3;21-chloro-9-fluoro-17-hydroxy-16-beta-methylpregna-1,4-diene,3,11,20-trione;molivate;pregna-1,4-diene-3,11,20-trione,21-chloro-9-fluoro-16-methyl-17-(1-oxobutoxy;sn203;21-chloro-9-fluoro-17-hydroxy-16beta-methylpregna-1,4-diene-3,11,20-trione 17-butyrate;ClobetasolPropionate-Bp/Ep/Usp
CAS:25122-57-0
MF:C26H32ClFO5
MW:478.98
EINECS:246-635-9
Product Categories:Intermediates & Fine Chemicals;Pharmaceuticals;Steroids;Organics
Mol File:25122-57-0.mol
Clobetasone butyrate Structure
Clobetasone butyrate Chemical Properties
Melting point 90-100°
Boiling point 573.3±50.0 °C(Predicted)
density 1.1736 (estimate)
storage temp. Refrigerator, Under Inert Atmosphere
solubility Practically insoluble in water, freely soluble in acetone and in methylene chloride, slightly soluble in ethanol (96 per cent).
form Solid
color White to Off-White
Stability:Stable. Combustible. Incompatible with strong oxidizing agents.
InChIKeyFBRAWBYQGRLCEK-JGSYYNBSNA-N
SMILES[C@]1(C(=O)CCl)(OC(=O)CCC)[C@@H](C)C[C@@]2([H])[C@]3([H])CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)C(=O)C[C@]12C |&1:0,11,14,16,26,28,33,r|
CAS DataBase Reference25122-57-0(CAS DataBase Reference)
Safety Information
Hazard Codes Xn
Risk Statements 40
Safety Statements 22-36
WGK Germany 3
RTECS TU4154083
HS Code 29372290
Toxicitymouse,LD50,intraperitoneal,500mg/kg (500mg/kg),Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 14, Pg. 838, 1983.
MSDS Information
Clobetasone butyrate Usage And Synthesis
Chemical PropertiesWhite or almost white powder.
UsesClobetasone butyrate is a synthetic glucocorticoid which is used as an anti-inflammatory in the treatment of various skin disorders. As a steroid medicine, it can used on the skin to treat swelling, itching and irritation. Such as eczema, including ;contact dermatitis; psoriasis; insect bites and stings; nappy rash.
DefinitionChEBI: Clobetasone butyrate is an organic molecular entity.
Mechanism of actionTopical corticosteroids (Clobetasone butyrate) inhibit the migration of macrophages and leukocytes into areas of inflamed skin by reversing vascular dilation and permeability, resulting in decreased erythema, edema and pruritus.
Side effectsSome people get a burning or stinging feeling for a few minutes when they put clobetasone cream or ointment on their skin. Clobetasone cream contains cetostearyl alcohol and chlorocresol, which may cause local skin reactions or allergic reactions.
Clobetasone butyrate Preparation Products And Raw materials
Tag:Clobetasone butyrate(25122-57-0) Related Product Information
Tributyrin Hexyl butyrate Butyric Acid Clobetasol Sodium Butyrate Isoamyl butyrate Epichlorohydrin Chloromethyl butyrate Clobetasol propionate CHLOROPHOSPHONAZO III Ethanone, 2-chloro-1-cyclopentyl- (9CI) 2-FLUOROCYCLOHEXANONE 1-Chlorohexadecane METHOXYMELONAL FEMA 3332 Clobetasone Chloroacetic acid 1-ACETOXY-3-CHLOROACETONE