EXO 1
| 中文名称 | EXO 1 |
|---|---|
| 中文同义词 | 2- [(4-氟苯甲酰基)氨基]苯甲酸甲酯;化合物EXO1;2-(4-氟苯甲酰氨基)苯甲酸甲酯 |
| 英文名称 | EXO1 |
| 英文同义词 | 4-FLUORO-BZ-2-ABZ-OME;2-(4-FLUOROBENZOYLAMINO)BENZOIC ACID METHYL ESTER;2-(4-FLUOROBENZOYLAMINO)METHYLBENZOATE;2-(4-Fluoro-benzoylami;2-(4-Fluorobenzoylamino)benzoic acid methyl ester, 2-(4-Fluorobenzoylamino)methylbenzoate;EOX 1;EXOCYTIC INHIBITOR 1;EXO1 |
| CAS号 | 75541-83-2 |
| 分子式 | C15H12FNO3 |
| 分子量 | 273.26 |
| EINECS号 | |
| 相关类别 | |
| Mol文件 | 75541-83-2.mol |
| 结构式 |  |
EXO 1 性质
| 储存条件 | +2C to +8C |
|---|---|
| 溶解度 | 在DMSO中的溶解度为19 mg/mL |
| 形态 | 固体 |
| 颜色 | 白色至米白色 |
Exo1 (2-(4-Fluorobenzoylamino)-benzoic acid methyl ester)是一种针对 exocytosis 的可逆抑制剂，可诱导 Golgi 迅速塌陷至内质网和来自高尔基体的 ADP-ribosylation factor (ARF) 1 的快速释放。
| Target | Value |
|
exocytosis
() | |
|
Golgi
() | |
|
ARF-1
() |
Exo1 is a modifier of Golgi ARF1 GTPase activity. Because Exo1 affects a subset of the membrane events that are blocked by BFA, but seems to have a different protein target (and presumably has different side effects), it provides an independent means to interfere with Golgi activity. Exo1 Disrupts Vesicular Traffic from the ER to the Golgi apparatus by disrupting Golgi structures. Exo1 inhibits exocytosis with an IC 50 of ~20 μM. Exo1 prevents acquisition of endoglycosidase H resistance by newly synthesized proteins such as VSVGts-GFP, transferrin, and MHC class I.
安全信息
| WGK Germany | 3 |
|---|
| 提供商 | 语言 |
|---|---|
|
英文
|
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2024/08/19 | S6800 | EXO 1 Exo1 | 75541-83-2 | 5mg | 390.25元 |
| 2023/03/20 | S6800 | EXO 1 Exo1 | 75541-83-2 | 25mg | 1265.48元 |