(5-PHENYL-2-UREIDO)THIOPHENE-3-CARBOXAMIDE 基本信息
中文名称 | (5-PHENYL-2-UREIDO)THIOPHENE-3-CARBOXAMIDE |
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中文同义词 | (5-苯基-2-脲基)噻吩-3-甲酰胺;(5-苯基-2-脲啶)噻吩-3-羧酰胺;IKK2抑制剂VI |
英文名称 | (5-PHENYL-2-UREIDO)THIOPHENE-3-CARBOXAMIDE |
英文同义词 | (5-PHENYL-2-UREIDO)THIOPHENE-3-CARBOXAMIDE;IKK-2 INHIBITOR VI;2-[(AMinocarbonyl)aMino]-5-phenyl-3-thiophenecarboxaMide;2-(carbamoylamino)-5-phenylthiophene-3-carboxamide;3-Thiophenecarboxamide, 2-[(aminocarbonyl)amino]-5-phenyl-;5-Phenyl-2-ureidothiophene-3-carboxylic Acid Amide;IKK2 Inhibitor VI,IKK-2 Inhibitor VI;5-Phenyl-2-ureidothiophene-3-carboxylic Acid Amide|||IKK2 Inhibitor IV |
CAS号 | 354811-10-2 |
分子式 | C12H11N3O2S |
分子量 | 261.3 |
EINECS号 | |
相关类别 | Aromatics Compounds;Aromatics;Inhibitors;Sulfur & Selenium Compounds;An ureido-thiophenecarboxamide compound that acts as a potent, cell-permeable, reversible, and ATP-competitive inhibitor of IKK-2 (IC50 = 13 nM). |
Mol文件 | Mol File |
结构式 |
(5-PHENYL-2-UREIDO)THIOPHENE-3-CARBOXAMIDE 性质
熔点 | >210°C (dec.) |
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沸点 | 445.6±45.0 °C(Predicted) |
密度 | 1.426±0.06 g/cm3(Predicted) |
储存条件 | Refrigerator |
溶解度 | 可溶于DMSO、甲醇(少许) |
酸度系数(pKa) | 14.00±0.70(Predicted) |
形态 | 固体 |
颜色 | 浅米色至浅棕色 |