| Company Name: |
J & K SCIENTIFIC LTD.
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| Tel: |
010-82848833 400-666-7788 |
| Email: |
jkinfo@jkchemical.com |
| Products Intro: |
Product Name:(5-Phenyl-2-ureido)thiophene-3-carboxaMide
CAS:354811-10-2
Package:2.5Mg,25Mg
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| Company Name: |
VDM Biochemicals
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| Tel: |
0330-2528181 |
| Email: |
sales@vdmbio.com |
| Products Intro: |
Product Name:IKK-2 Inhibitor VI
CAS:354811-10-2
Purity:>=98%
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| Company Name: |
Chemsky (shanghai) International Co.,Ltd
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| Tel: |
021-50135380 |
| Email: |
shchemsky@sina.com |
| Products Intro: |
Product Name:(5-Phenyl-2-ureido)thiophene-3-carboxaMide;2-[(AMinocarbonyl)aMino]-5-phenyl-3-thiophenecarboxaMide
CAS:354811-10-2
Purity:98+% Package:1Mg;5Mg;10Mg;50Mg;100Mg;500Mg
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| | (5-PHENYL-2-UREIDO)THIOPHENE-3-CARBOXAMIDE Basic information |
| | (5-PHENYL-2-UREIDO)THIOPHENE-3-CARBOXAMIDE Chemical Properties |
| Melting point | >210°C (dec.) | | Boiling point | 445.6±45.0 °C(Predicted) | | density | 1.426±0.06 g/cm3(Predicted) | | storage temp. | Refrigerator | | solubility | DMSO, Methanol (Slightly) | | pka | 14.00±0.70(Predicted) | | form | Solid | | color | Light Beige to Light Brown |
| | (5-PHENYL-2-UREIDO)THIOPHENE-3-CARBOXAMIDE Usage And Synthesis |
| Description | Inhibitor of NF-κB kinase 2 (IKK2, also known as IKKβ) acts as part of an IKK complex in the canonical NF-κB pathway, phosphorylating inhibitors of NF-κB (IκBs) to initiate signaling. NF-κB signaling can also occur through a non-canonical, IKK/IκB-independent pathway. IKK2 Inhibitor VI is a potent, cell-permeable, reversible inhibitor of IKK2 (IC50 = 13 nM). It is used to evaluate the role of the canonical, IκB-dependent NF-κB signaling pathway in cellular responses. | | Uses | (5-PHENYL-2-UREIDO)THIOPHENE-3-CARBOXAMIDE is an inhibitor of NF-κB kinase 2 (IKK2, also known as IKKβ) acts as part of an IKK complex in the canonical NF-κB pathway, phosphorylating inhibitors of NF-κB (IκBs) to initiate signaling. NF-κB signaling can also occur through a non-canonical, IKK/IκB-independent pathway. IKK2 Inhibitor VI is a potent, cell-permeable, reversible inhibitor of IKK2 (IC50 = 13 nM). It is used to evaluate the role of the canonical, IκB-dependent NF-κB signaling pathway in cellular responses. | | Uses | An ureido-thiophenecarboxamide compound that acts as a potent inhibitor of IKK-2 (InhibitorVI). |
| | (5-PHENYL-2-UREIDO)THIOPHENE-3-CARBOXAMIDE Preparation Products And Raw materials |
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