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ChemicalBook > Product Catalog >Analytical Chemistry >Standard >Pharmaceutical Impurity Reference Standards >Benzonitrile, 4,4'-[[2,2'-bis(hydroxymethyl)[1,1'-biphenyl]-4,4'-diyl]bis(oxy)]bis-

Benzonitrile, 4,4'-[[2,2'-bis(hydroxymethyl)[1,1'-biphenyl]-4,4'-diyl]bis(oxy)]bis-

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Benzonitrile, 4,4'-[[2,2'-bis(hydroxymethyl)[1,1'-biphenyl]-4,4'-diyl]bis(oxy)]bis- Suppliers list
Company Name: Guangzhou CATO Research Chemicals Inc.
Tel: +86-020-81960175-617 +8615602392859
Email: Intermediate@cato-chem.com
Products Intro: Product Name:Crisaborole Impurity 38
CAS:2254541-79-0
Purity:0.99 Package:25MG;50MG;100MG
Company Name: Moxin Chemicals
Tel: +8617320513646
Email: mike@molcoo.com
Products Intro: Product Name:2254541-79-0
CAS:2254541-79-0
Purity:98 Package:20mg，100mg，1g Remarks:Real inventory，drug impurities，drug standards
Company Name: QUALITY CONTROL SOLUTIONS LTD.
Tel: 0755-66853366; 13670046396
Email: ORDERS@QCSRM.COM
Products Intro: Product Name:Crisaborole Impurity 11
CAS:2254541-79-0
Purity:0.95 Package:10mg; 25mg;50mg;100mg Remarks:Brand: QCS; Can provide COA, hydrogen spectrum, mass spectrometry, liquid phase; Level: Pharmaceutical Impurity Standard
Company Name: S.Z. PhyStandard Bio-Tech. Co., Ltd.  
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Products Intro: Product Name:Benzonitrile, 4,4'-[[2,2'-bis(hydroxymethyl)[1,1'-biphenyl]-4,4'-diyl]bis(oxy)]bis-
CAS:2254541-79-0
Purity:95% HPLC Package:10mg;25mg;50mg
Company Name: Beijing Comparison Pharmaceutical Technology Co., Ltd  
Tel: 010-010-52878169 15801002657
Email: sales@bjcomparison.com
Products Intro: Product Name:4,4'-((2,2'-bis(hydroxymethyl)-[1,1'-biphenyl]-4,4'-diyl)bis(oxy))dibenzonitrile
CAS:2254541-79-0
Purity:≥98% Package:100mg
Benzonitrile, 4,4'-[[2,2'-bis(hydroxymethyl)[1,1'-biphenyl]-4,4'-diyl]bis(oxy)]bis- Basic information
Product Name:Benzonitrile, 4,4'-[[2,2'-bis(hydroxymethyl)[1,1'-biphenyl]-4,4'-diyl]bis(oxy)]bis-
Synonyms:Benzonitrile, 4,4'-[[2,2'-bis(hydroxymethyl)[1,1'-biphenyl]-4,4'-diyl]bis(oxy)]bis-;4-((2,2'-bis(hydroxymethyl)-4'-(4-isocyanophenoxy)-[1,1'-biphenyl]-4-yl)oxy)benzonitrile;Crisaborole Diamer;Crisaborole Dimer ImpurityQ: What is Crisaborole Dimer Impurity Q: What is the CAS Number of Crisaborole Dimer Impurity;4,4'-((2,2'-bis(hydroxymethyl)-[1,1'-biphenyl]-4,4'-diyl)bis(oxy))dibenzonitrile;Benzonitrile, 4,4'-[[2,2'-bis(hydroxymethyl)[1,1'-biphenyl]-4,4'-diyl]bis(oxy)]bis-
CAS:2254541-79-0
MF:C28H20N2O4
MW:448.47
EINECS:
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Mol File:2254541-79-0.mol
Benzonitrile, 4,4'-[[2,2'-bis(hydroxymethyl)[1,1'-biphenyl]-4,4'-diyl]bis(oxy)]bis- Structure
Benzonitrile, 4,4'-[[2,2'-bis(hydroxymethyl)[1,1'-biphenyl]-4,4'-diyl]bis(oxy)]bis- Chemical Properties
Boiling point 702.3±60.0 °C(Predicted)
density 1.37±0.1 g/cm3(Predicted)
pka13.95±0.10(Predicted)
Safety Information
MSDS Information
Benzonitrile, 4,4'-[[2,2'-bis(hydroxymethyl)[1,1'-biphenyl]-4,4'-diyl]bis(oxy)]bis- Usage And Synthesis
UsesCrisaborole Diamer Impurity is an impurity of Crisaborole (H947928). Crisaborole is a series of phenoxy benzoxaboroles were synthesized and screened for their inhibitory activity against PDE4 and cytokine release. 5-?(4-?Cyanophenoxy)?-?2,?3-?dihydro-?1-?hydroxy-?2,?1-?benzoxaborole (AN2728) showed potent activity both in vitro and in vivo. AN2728 is being studied as an anti-inflammatory agent.
Benzonitrile, 4,4'-[[2,2'-bis(hydroxymethyl)[1,1'-biphenyl]-4,4'-diyl]bis(oxy)]bis- Preparation Products And Raw materials
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