zipeprol

zipeprol Basic information
Product Name:zipeprol
Synonyms:zipeprol;α-(α-Methoxybenzyl)-4-(β-methoxyphenethyl)-1-piperazineethanol;34758-84-4 (Di-hydrochloride);4-(2-Methoxy-2-phenylethyl)-alpha-(methoxyphenylmethyl)-1-piperazineethanol;Einecs 252-191-7;Unii-G5muv8139h;Zipeprolum;Zipeprolum [inn-latin]
CAS:34758-83-3
MF:C23H32N2O3
MW:384.52
EINECS:252-191-7
Product Categories:
Mol File:34758-83-3.mol
zipeprol Structure
zipeprol Chemical Properties
Melting point 83°
Boiling point 507.7±50.0 °C(Predicted)
density 1.108±0.06 g/cm3(Predicted)
pka13.97±0.20(Predicted)
Safety Information
DEA Controlled SubstancesCSCN: 9873
CSA SCH: Schedule I
NARC: Yes
MSDS Information
zipeprol Usage And Synthesis
OriginatorRespilene,Winthrop,France,1973
DefinitionChEBI: Zipeprol is a benzyl ether.
Manufacturing ProcessIn a reactor provided with a mechanical stirrer, a reflux refrigerant and a thermometer, there is introduced: 393 grams 1-[2-phenyl, 2-methoxy]ethyl piperazine and 22 grams 3-phenyl-3-methoxy propylene oxide in 750 ml of absolute ethanol.
When the slightly exothermic reaction (rise in temperature of about 20°C) has ceased, heating is effected for 1.5 hours at 60°C. The product is then cooled to 4°C and left to crystallize for about 12 hours. The precipitate is centrifugated then recrystallized in 500 ml of absolute ethanol.
420 grams of the desired compound is thus obtained in the form of a white, crystalline powder, melting point 83°C.
Brand nameAntitaxil-z;Antituxil-z;Balutox;Broncozina;Bronx;Cerm-3024;Citizeta;Mirsol;Ogyline;Respilene;Respirase;Respirex;Santus;Talasa;Zitoxil.
Therapeutic FunctionBronchodilator
zipeprol Preparation Products And Raw materials
Tag:zipeprol(34758-83-3) Related Product Information
eprozinol 1,4-BIS(2-HYDROXYETHYL)PIPERAZINE Zipeprol dihydrochloride zipeprol CHEMPACIFIC 41241