|
|
| | 2-Deoxy-2-fluoro-L-fucose Basic information |
| Product Name: | 2-Deoxy-2-fluoro-L-fucose | | Synonyms: | 2-Deoxy-2-fluoro-L-fucose;(3S,4R,5S,6S)-3-Fluoro-6-methyl-tetrahydropyran-2,4,5-triol;2-Deoxy-2-fluoro-L-fucose, Min. 98%;L-Galactose, 2,6-dideoxy-2-fluoro-;2,6-dideoxy-2-fluoro-L-Galactose;(2S,3R,4R,5S)-2-Fluoro-3,4,5-trihydroxyhexanal;2-Deoxy-2-fluoro-L-fucose, CAS NO: 70763-62-1;2-fluorofucose | | CAS: | 70763-62-1 | | MF: | C6H11FO4 | | MW: | 166.15 | | EINECS: | | | Product Categories: | Pharm intermediate | | Mol File: | 70763-62-1.mol |  |
| | 2-Deoxy-2-fluoro-L-fucose Chemical Properties |
| Boiling point | 386.5±42.0 °C(Predicted) | | density | 1.335±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMF: 20 mg/ml; DMSO: 30 mg/ml; Ethanol: 0.25 mg/ml; PBS (pH 7.2): 10 mg/ml | | form | A crystalline solid | | pka | 12.70±0.20(Predicted) | | color | White to off-white |
| | 2-Deoxy-2-fluoro-L-fucose Usage And Synthesis |
| Uses | Fucose is a deoxyhexose that is present in many organisms. Fucose-containing glycans, generated by fucosyltransferase using GDP-fucose, have roles in cell signaling, cell-cell interactions, and blood properties. 2-deoxy-2-fluoro L-Fucose is a fluorinated fucose analog. It can be metabolized inside the cell to a substrate-based inhibitor of fucosyltransferases. Alternatively, it can be converted in vitro to GDP-2-deoxy-2-fluoro L-fucose, a competitive inhibitor of α1,3-fucosyltransferase V (Ki = 4.2 μM). | | Uses | 2-Deoxy-2-fluoro-L-fucose is a useful compound in the area of cancer treatment. as it has been used in adoptive cell therapy. |
| | 2-Deoxy-2-fluoro-L-fucose Preparation Products And Raw materials |
|