Company Name: |
J & K SCIENTIFIC LTD.
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Tel: |
010-82848833 400-666-7788 |
Email: |
jkinfo@jkchemical.com |
Products Intro: |
Product Name:Nucleocidin CAS:24751-69-7 Package:10Mg,25Mg,50Mg
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| nucleocidin Basic information |
| nucleocidin Chemical Properties |
Melting point | >190° (dec) | Boiling point | 747.6±70.0 °C(Predicted) | density | 2.23±0.1 g/cm3(Predicted) | storage temp. | Store at -20°C | solubility | Soluble in DMSO | pka | 9.15±0.70(Predicted) |
Toxicity | LD50 i.p. in mice: ~0.2 mg/kg (Thomas) |
| nucleocidin Usage And Synthesis |
Uses | Nucleocidin is used in studies relating to novel parasite inhibitors. | Definition | ChEBI: Nucleocidin is a nucleoside antibiotic that is 5'-O-sulfamoyladenosine in which the hydrogen atom at position 4' is replaced by a fluorine atom. It is a natural product synthesized by several Streptomyces species. It exhibits broad spectrum antibacterial activity, and also has a strong effect against Trypanosoma brucei, the protozoan parasite responsible for the African sleeping sickness. It has a role as a bacterial metabolite, an antibacterial agent, a trypanocidal drug, a protein synthesis inhibitor and a nucleoside antibiotic. It is a member of adenosines, an organofluorine compound, a sulfamate ester, a member of 6-aminopurines and a diol. It is functionally related to an adenosine. |
| nucleocidin Preparation Products And Raw materials |
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