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| | 3-(BENZYLAMINO)PROPIONITRILE Basic information |
| | 3-(BENZYLAMINO)PROPIONITRILE Chemical Properties |
| Melting point | 70 °C | | Boiling point | 276.13°C (rough estimate) | | density | 1.024 g/mL at 25 °C (lit.) | | refractive index | n20/D 1.5308(lit.) | | Fp | >230 °F | | storage temp. | Refrigerator | | solubility | Soluble in DMSO. | | form | Liquid | | pka | 7.29±0.19(Predicted) | | color | Clear Colorless | | Specific Gravity | 1.024 | | CAS DataBase Reference | 706-03-6 |
| Hazard Codes | Xn,Xi | | Risk Statements | 20/21/22-36/37/38 | | Safety Statements | 26-37/39 | | RIDADR | UN3276 | | WGK Germany | 3 | | HazardClass | 6.1 | | PackingGroup | III | | HS Code | 29269095 |
| | 3-(BENZYLAMINO)PROPIONITRILE Usage And Synthesis |
| Chemical Properties | CLEAR COLOURLESS LIQUID | | Uses | 3-(Benzylamino)propionitrile was used as starting reagent in the synthesis of:
- (3R,4S)-1-benzyl-4-phenylpyrrolidine-3-carboxylic acid, key chiral building block for synthesis of biologically active compounds
- 1-{[benzyl-(2-cyano-ethyl)-amino]-methyl}-5-methyl-1H-pyrazole-3-carboxylic acid ethyl ester
- 3-[benzyl-(3,5-dimethyl-pyrazol-1-ylmethyl)-amino]-propionitrile
| | Uses | 3-(BenzylaMino)propionitrile is used in the michael addition of primary and secondary amines to acrylonitrile catalyzed by lipases. | | Application | 3-(Benzylamino)propionitrile was used as starting reagent in the synthesis of:
(3R,4S)-1-benzyl-4-phenylpyrrolidine-3-carboxylic acid, key chiral building block for synthesis of biologically active compounds
1-{[benzyl-(2-cyano-ethyl)-amino]-methyl}-5-methyl-1H-pyrazole-3-carboxylic acid ethyl ester
3-[benzyl-(3,5-dimethyl-pyrazol-1-ylmethyl)-amino]-propionitrile | | General Description | 3-(Benzylamino)propionitrile undergoes aza-type Michael reaction with 1-hydroxymethyl-5-methyl-1H-pyrazole-3-carboxylic acid ethyl ester under mild conditions. |
| | 3-(BENZYLAMINO)PROPIONITRILE Preparation Products And Raw materials |
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