| Company Name: |
BOC Sciences
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| Tel: |
16314854226 |
| Email: |
info@bocsci.com |
| Products Intro: |
Product Name:CAY10412
CAS:390824-17-6
Purity:98% Package:1G;10G;100G Remarks:Anandamide (AEA), also known as N-arachidonoylethanolamine, is an endogenous lipid with cannabinergic activity. CAY10412 is an analog of AEA that has no intrinsic binding affinity for either CB1 or CB
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| Company Name: |
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
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| Tel: |
18818260767 |
| Email: |
sales@chemegen.com |
| Products Intro: |
Product Name:CAY10412
CAS:390824-17-6
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
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| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
4008200310 |
| Email: |
marketing@tsbiochem.com |
| Products Intro: |
Product Name:CAY10412;CAY-10412
CAS:390824-17-6
Purity:98% Package:200 mg
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| Company Name: |
Cayman Chemical Company
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| Tel: |
(800) 364-9897 |
| Email: |
cayman@caymanchem.com |
| Products Intro: |
Product Name:CAY10412
CAS:390824-17-6
Package:>98% Remarks:72620
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| | CAY10412 Basic information |
| Product Name: | CAY10412 | | Synonyms: | CAY10412;5Z,8Z,11Z,14Z-EICOSATETRAENOIC ACID, 3-THIENYLMETHYL ESTER;YOPBWSZRYHDZAA-DOFZRALJSA-N;CAY10412 Exclusive;5,8,11,14-Eicosatetraenoic acid, 3-thienylmethyl ester, (5Z,8Z,11Z,14Z)- | | CAS: | 390824-17-6 | | MF: | C25H36O2S | | MW: | 400.62 | | EINECS: | | | Product Categories: | | | Mol File: | 390824-17-6.mol |  |
| | CAY10412 Chemical Properties |
| storage temp. | Store at -20°C | | solubility | DMF: 30 mg/ml; DMSO: 20 mg/ml; Ethanol: 30 mg/ml; Ethanol:PBS (pH 7.2) (1:3): 100 μg/ml |
| | CAY10412 Usage And Synthesis |
| Uses | Anandamide (arachidonoyl ethanolamide; AEA) is an endogenous lipid with cannabinergic activity; along with 2-arachidonoyl glycerol, it forms part of the endocannabinoid system. AEA undergoes reuptake into neurons by a facilitated process. Controversy exists as to whether there is a specific AEA transporter, or instead the uptake process is simply driven by hydrolysis of AEA by intracellular fatty acyl amide hydrolase (FAAH). CAY10412 is an analog of AEA that has no intrinsic binding affinity for either CB1 or CB2 receptors. It is a potent inhibitor of AEA reuptake in U937 lymphoma cells, with an IC50 of 3 μM. CAY10412 could be a useful tool for distinguishing the competing transporter theories. The pharmacology of CAY10412 is largely unexplored; it may enhance endocannabinoid signalling by augmenting endocannabinoid concentrations. |
| | CAY10412 Preparation Products And Raw materials |
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