| Company Name: |
BOC Sciences
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| Tel: |
16314854226 |
| Email: |
info@bocsci.com |
| Products Intro: |
Product Name:CAY10554
CAS:267654-00-2
Purity:95% Package:1G;10G;100G Remarks:Cyclin-dependent kinases (CDKs) are the families of protein kinases first discovered for their role in regulating the cell cycle. They are also involved in regulating transcription, mRNA processing, a
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| Company Name: |
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
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| Tel: |
18818260767 |
| Email: |
sales@chemegen.com |
| Products Intro: |
Product Name:CAY10554
CAS:267654-00-2
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
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| | BML-259 Basic information |
| Product Name: | BML-259 | | Synonyms: | BML-259;CAY10554;2-phenyl-N-(5-propan-2-yl-1,3-thiazol-2-yl)acetamide;Benzeneacetamide, N-[5-(1-methylethyl)-2-thiazolyl]-;BML-259,protein,p53,CDK,death,disease,neurotoxicity,cell,Inhibitor,inhibit,Cyclin dependent kinase,Alzheimer's | | CAS: | 267654-00-2 | | MF: | C14H16N2OS | | MW: | 260.35 | | EINECS: | | | Product Categories: | | | Mol File: | 267654-00-2.mol |  |
| | BML-259 Chemical Properties |
| Melting point | 150-152℃ | | storage temp. | RT | | solubility | Soluble in DMSO (up to 25 mg/ml). | | form | White solid. | | color | white | | Stability: | Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months. |
| | BML-259 Usage And Synthesis |
| Description | BML-259 (267654-00-2) is a potent inhibitor of Cdk5/p25 (IC50 = 64 nM) and Cdk2 (IC50 = 98nM).1 | | Definition | ChEBI: 2-phenyl-N-(5-propan-2-yl-2-thiazolyl)acetamide is a member of acetamides. | | References | 1) Helal et al. (2004) Discovery and SAR of 2-aminothiazole inhibitors of cyclin-dependent kinase 5/p25 as a potential treatment for Alzheimer’s disease; Bioorg. Med. Chem. Lett. 14 5521 |
| | BML-259 Preparation Products And Raw materials |
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