| Company Name: |
3B Pharmachem (Wuhan) International Co.,Ltd.
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| Tel: |
821-50328103-801 18930552037 |
| Email: |
3bsc@sina.com |
| Products Intro: |
Product Name:UCB 35625;1,4-trans-1-(1-Cycloocten-1-ylMethyl)-4-[[(2,7-dichloro-9H-xanthen-9-yl)carbonyl]aMino]-1-ethylpiperidiniuMiodide
CAS:301648-08-8
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g
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| Company Name: |
EMMX Biotechnology LLC
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| Tel: |
888-539-0666 |
| Email: |
info@emmx.com |
| Products Intro: |
Product Name:UCB 35625
CAS:301648-08-8
Purity:98% HPLC Package:5mg;10mg;25mg;50mg;100mg;250mg;500mg;1g
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| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
4008200310 |
| Email: |
marketing@tsbiochem.com |
| Products Intro: |
Product Name:UCB 35625;UCB 35625
CAS:301648-08-8
Purity:98% Package:50 mg
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| Company Name: |
ApexBio Technology
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| Tel: |
+ 1-832-696-8203 |
| Email: |
sales@apexbt.com |
| Products Intro: |
Product Name:UCB 35625
CAS:301648-08-8
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| | 1,4-TRANS-1-(1-CYCLOOCTEN-1-YLMETHYL)-4-[[(2,7-DICHLORO-9H-XANTHEN-9-YL)CARBONYL]AMINO]-1-ETHYLPIPERIDINIUM IODIDE Basic information |
| | 1,4-TRANS-1-(1-CYCLOOCTEN-1-YLMETHYL)-4-[[(2,7-DICHLORO-9H-XANTHEN-9-YL)CARBONYL]AMINO]-1-ETHYLPIPERIDINIUM IODIDE Chemical Properties |
| storage temp. | Store at +4°C | | solubility | <32.77mg/ml in ethanol; <65.54mg/ml in DMSO |
| | 1,4-TRANS-1-(1-CYCLOOCTEN-1-YLMETHYL)-4-[[(2,7-DICHLORO-9H-XANTHEN-9-YL)CARBONYL]AMINO]-1-ETHYLPIPERIDINIUM IODIDE Usage And Synthesis |
| Uses | UCB 35625 is an antagonist of CCR1, which are receptors prevalent in chronic inflammatory processes. UCB 35625 displays antiarthritic activity and is also a selective antagonist of CCR3. | | Biological Activity | Potent chemokine CCR1 and CCR3 receptor antagonist. Inhibits MIP-1 α -induced chemotaxis in CCR1 transfectants and eotaxin-induced chemotaxis in CCR3 transfectants (IC 50 values are 9.57 and 93.8 nM respectively). Antagonizes CCR3-mediated entry of HIV-1 isolate 89.6 into NP-2 cells (IC 50 = 57 nM). Isomer of J 113863 (1,4-cis-1-(1-Cycloocten-1-ylmethyl)-4-[[(2,7-dichloro-9H-xanthen-9-yl)carbonyl]amino]-1-ethylpiperidiniumiodide ). |
| | 1,4-TRANS-1-(1-CYCLOOCTEN-1-YLMETHYL)-4-[[(2,7-DICHLORO-9H-XANTHEN-9-YL)CARBONYL]AMINO]-1-ETHYLPIPERIDINIUM IODIDE Preparation Products And Raw materials |
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