Company Name: |
MedChemexpress LLC
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021-58955995 |
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sales@medchemexpress.cn |
Products Intro: |
Product Name:CP 316311 CAS:175139-41-0 Purity:>98% Package:5800RMB/1mg
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Company Name: |
ShangHai Caerulum Pharma Discovery Co., Ltd.
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Tel: |
18149758185 |
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sales-cpd@caerulumpharma.com |
Products Intro: |
Product Name:3,6-dimethyl-4-pentan-3-yloxy-2-(2,4,6-trimethylphenoxy)pyridine CAS:175139-41-0 Purity:98% Package:1g;10g;100g
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Company Name: |
BOC Sciences
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Tel: |
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Email: |
info@bocsci.com |
Products Intro: |
Product Name:CP-316311 CAS:175139-41-0 Purity:98% Remarks:CP-316311, a pyridine derivative, has been found to be a CRF 1 receptor antagonist and was once studied as an antidepressant agent by Pfizer. IC50: 6.8 nM.
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| CP 316311 Basic information |
Product Name: | CP 316311 | Synonyms: | CP 316311;Pyridine, 4-(1-ethylpropoxy)-3,6-dimethyl-2-(2,4,6-trimethylphenoxy)-;3,6-dimethyl-4-pentan-3-yloxy-2-(2,4,6-trimethylphenoxy)pyridine;CP-316 | CAS: | 175139-41-0 | MF: | C21H29NO2 | MW: | 327.46 | EINECS: | | Product Categories: | | Mol File: | 175139-41-0.mol | ![CP 316311 Structure](CAS/20200611/GIF/175139-41-0.gif) |
| CP 316311 Chemical Properties |
Melting point | 72.5-74 °C | Boiling point | 413.9±40.0 °C(Predicted) | density | 1.007±0.06 g/cm3(Predicted) | storage temp. | Store at -20°C | solubility | Soluble in DMSO | pka | 5.63±0.30(Predicted) |
| CP 316311 Usage And Synthesis |
Biological Activity | CP 316311 is a potent and selective CRF1 receptor antagonist with IC50 of 6.8 nM. | in vitro | CP 316311 fully antagonizes CRF-stimulated adenylate cyclase activity in rat cortex and at human CRF1 receptors endogenously expressed in IMR32 cells with apparent K i values of 7.6 and 8.5 nM, respectively. < /p> | target | IC50: 6.8 nM (CRF1 receptor) |
| CP 316311 Preparation Products And Raw materials |
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