- 5-chloro-2,3-diphenylpyrazine
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- $8.00 / 1kg
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2024-04-24
- CAS:41270-66-0
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: g-kg-tons, free sample is available
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| 5-chloro-2,3-diphenylpyrazine Basic information |
| 5-chloro-2,3-diphenylpyrazine Chemical Properties |
Melting point | 126-128℃ (methanol ) | Boiling point | 145°C/0.001mmHg(lit.) | density | 1?+-.0.06 g/cm3(Predicted) | pka | -2.16±0.10(Predicted) | form | powder to crystal | color | White to Orange to Green | InChI | InChI=1S/C16H11ClN2/c17-14-11-18-15(12-7-3-1-4-8-12)16(19-14)13-9-5-2-6-10-13/h1-11H | InChIKey | VUGNCPVAXWZTOL-UHFFFAOYSA-N | SMILES | C1(C2=CC=CC=C2)=NC=C(Cl)N=C1C1=CC=CC=C1 | CAS DataBase Reference | 41270-66-0 |
| 5-chloro-2,3-diphenylpyrazine Usage And Synthesis |
Uses | 2-Chloro-5,6-diphenylpyrazine is a diphenylpyrazine derivative used in a study to determine a novel class of prostacyclin receptor agonists. | Synthesis |
50 gm of 2-hydroxy-5,6-diphenylpyrazine obtained was treated with 250 ml of POCI3 and then heated the reaction mixture at 100-110 °C with stirring for 5-6 hrs. The reaction mixture was cooled to room temperature and poured in 1000 ml of ice water at 0-5 °C and maintained with stirring for 60 minutes. The solid obtained was filtered, washed with water and dried to obtain 41.3 gm of 5-chloro-2,3-diphenylpyrazine. Yield: 77.00 percent.
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| 5-chloro-2,3-diphenylpyrazine Preparation Products And Raw materials |
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