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Product Name:LEUKOTRIENE D4
CAS:73836-78-9
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g
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Shanghai Aladdin Bio-Chem Technology Co.,LTD
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Product Name:Leukotriene D4
CAS:73836-78-9
Purity:97%,100 ug/mL in ethanol Package:50μg/RMB 5629.90;25μg/RMB 3089.90
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Guangzhou Isun Pharmaceutical Co., Ltd
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Product Name:Leukotriene D4
CAS:73836-78-9
Purity:97.0% Package:5MG; 25MG; 100MG; 1G
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Sigma-Aldrich
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Product Name:Leukotriene D4
CAS:73836-78-9
Purity:>=97% Package:10μg, 25μg, 50μg, 250μg Remarks:L5011
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| | LEUKOTRIENE D4 Basic information |
| Product Name: | LEUKOTRIENE D4 | | Synonyms: | (r-(r*,s*-(e,e,z,z)))-inyl);glycine,n-(s-(1-(4-carboxy-1-hydroxybutyl)-2,4,6,9-pentadecatetraenyl)-l-cyste;leukotriened;leukotriened(sub4);(5S,6R,7E,9E,11E,14E)-6-[2-amino-2-(carboxymethylcarbamoyl)ethyl]sulfanyl-5-hydroxy-icosa-7,9,11,14-tetraenoic acid;LEUKOTRIENE D4 (ETHANOL SOLUTION);N-[S-[(1R,2E,4E,6Z,9Z)-1-[(1S)-1-Hydroxy-4-carboxybutyl]-2,4,6,9-pentadecatetraene-1-yl]-L-cysteinyl]glycine;N-[S-[(1R,2E,4E,6Z,9Z)-1-[(1S)-1-Hydroxy-4-carboxybutyl]-2,4,6,9-pentadecatetren-1-yl]-L-cysteinyl]glycine | | CAS: | 73836-78-9 | | MF: | C25H40N2O6S | | MW: | 496.66 | | EINECS: | | | Product Categories: | Arachidonic Acid Cascade;Fatty Acids;Leukotrienes;LeukotrienesLipids;Lipids in Cell Signaling | | Mol File: | 73836-78-9.mol |  |
| | LEUKOTRIENE D4 Chemical Properties |
| Boiling point | 785.8±60.0 °C(Predicted) | | density | 1.162±0.06 g/cm3(Predicted) | | Fp | 9℃ | | storage temp. | -70°C | | solubility | A solution in ethanol | | form | Liquid. | | pka | 3.03±0.10(Predicted) | | color | Colorless to light yellow |
| | LEUKOTRIENE D4 Usage And Synthesis |
| Description | Leukotriene D4 (LTD4) is an active metabolite of LTC4 (Item Nos. 20210 | 10007241) and a constituent of slow-reacting substance of anaphylaxis (SRS-A). It is formed via metabolism of LTC4 by γ-glutamyl transpeptidase. Like LTC4, LTD4 (0.01-0.1 pM) induces contractions in isolated guinea pig parenchymal strips and tracheal spirals. In vivo, LTD4 increases insufflation pressure, a marker of bronchoconstriction, in anesthetized guinea pigs by 100% when administered at a dose of 89 pmol per animal. It also increases vascular permeability in guinea pig skin when administered intradermally at a dose of 0.1 pmol per animal. | | Uses | LTD4 (Leukotriene D4) is a member of the leukotriene family shown to be a potent contractor of smooth muscle. | | Definition | ChEBI: A leukotriene that is (7E,9E,11Z,14Z)-icosa-7,9,11,14-tetraenoic acid substituted by a hydroxy group at position 5 (5S) and a L-cysteinylglycinyl group at
position 6 (6R). | | Biochem/physiol Actions | Slow reacting substance of anaphylaxis (SRS-A). Potent bronchoconstrictor and mediator of asthmatic and inflammatory processes. Increases cytosolic free Ca2+ in epithelial cells. |
| | LEUKOTRIENE D4 Preparation Products And Raw materials |
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