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| | 3-ethylbicyclo[3.2.0]hept-3-en-6-one Basic information |
| | 3-ethylbicyclo[3.2.0]hept-3-en-6-one Chemical Properties |
| Boiling point | 212.5±9.0 °C(Predicted) | | density | 1.043±0.06 g/cm3(Predicted) |
| | 3-ethylbicyclo[3.2.0]hept-3-en-6-one Usage And Synthesis |
| Uses | 3-ethylbicyclo[3.2.0]hept-3-en-6-one is an important organic compound mainly used in chemical research. Currently, it is mainly used to study the separation of its enantiomers. | | Synthesis | 3-ethylbicyclo[3.2.0]hept-3-en-6-one was synthesised from 4-Ethyl-3-hydroxyhept-6-enoic acid.
Preparation method: Intermediate (39.0 g, 226 mmol), acetic anhydride (195 mL), potassium acetate (51.4 g, 542 mmol) were added to the reaction flask, and the reaction was stirred at room temperature for 1 h, and the temperature was raised to 130 °C,The reaction was stirred for 4h, and the reaction was completed by GC monitoring. Add H2O (200mL), extract with EA (200mL*3), wash with 1N NaOH (100mL) and water (200mL), dry over anhydrous Na2SO4, filter, spin-dried to obtain the crude product of 3-ethylbicyclo[3.2.0]hept-3-en-6-one, and distilled under high vacuum to obtain 16g of 3-ethylbicyclo[3.2.0]hept-3-en-6-one , the appearance is colorless to light yellow oily liquid, the yield is 51.6%.
![3-ethylbicyclo[3.2.0]hept-3-en-6-one synthesis](/NewsImg/2023-11-24/6383643757173721588598819.png "3-ethylbicyclo[3.2.0]hept-3-en-6-one synthesis") |
| | 3-ethylbicyclo[3.2.0]hept-3-en-6-one Preparation Products And Raw materials |
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