- 1-Methylimidazole
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- $100.00/ kg
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2024-08-24
- CAS:616-47-7
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 5000
- 1-Methylimidazole
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- $10.00/ kg
-
2024-08-23
- CAS:616-47-7
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 10 tons
- 1-Methylimidazole
-
- $6.00 / 1kg
-
2024-08-23
- CAS:616-47-7
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 2000KG/Month
Related articles - 1-Methylimidazole: An Overview
- 1-Methylimidazole, also known as N-methylimidazole, is a heterocyclic organic compound with the molecular formula C4H6N2.
- Jul 12,2024
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| 1-Methylimidazole Basic information |
| 1-Methylimidazole Chemical Properties |
Melting point | −60 °C(lit.) | Boiling point | 198 °C(lit.) | density | 1.03 g/mL at 25 °C(lit.) | vapor pressure | 0.4 mm Hg ( 20 °C) | refractive index | n20/D 1.495(lit.) | Fp | 198 °F | storage temp. | Store below +30°C. | solubility | Chloroform (Slightly), Methanol (Slightly) | form | Liquid | pka | 6.95(at 25℃) | Specific Gravity | 1.031 | color | Clear colorless to yellow | PH | 9.5-10.5 (50g/l, H2O, 20℃) | PH Range | 9.5 - 11.5 at 100 g/l at 20 °C | explosive limit | 2.7-15.7%(V) | Water Solubility | Miscible with water. | Sensitive | Hygroscopic | BRN | 105197 | Stability: | Stable, but moisture sensitive. Incompatible with acids, acid anhydrides, strong oxidizing agents, moisture, carbon dioxide, acid chlorides. | InChIKey | MCTWTZJPVLRJOU-UHFFFAOYSA-N | LogP | -0.19 at 25℃ | CAS DataBase Reference | 616-47-7(CAS DataBase Reference) | NIST Chemistry Reference | 1H-Imidazole, 1-methyl-(616-47-7) | EPA Substance Registry System | 1H-Imidazole, 1-methyl- (616-47-7) |
| 1-Methylimidazole Usage And Synthesis |
Chemical Properties | 1-Methylimidazole or N-methylimidazole is an aromatic heterocyclic organic compound with the formula CH3C3H3N2. It is a colorless to yellow liquid, with an amine-like odor. It is miscible with water. N-methylimidazole is an important raw material for the synthesis of pharmaceutical intermediates, used in the preparation of losartan, nizofenone, 1-Methyl-1H-imidazole-5-carbonyl chloride hydrochloride and naphazoline hydrochloride, etc. It is also used as a specialty solvent, a base, and as a precursor to some ionic liquids. | Uses | 1-Methylimidazole is used as a precursor for the synthesis of pyrrole-imidazole polyamides, ionic liquids such as 1-butyl-3-methylimidazolium hexafluorophosphate. It is actively involved in removing acid during the production of diethoxyphenylphosphine. It is used as an intermediate in organic synthesis. | Uses | 1-Methylimidazole is an aprotic solvent. It is a derivative of imidazole used in the production of pharmaceuticals, pesticides, ion exchange resins, dye intermediates, textile auxiliaries, photographic chemicals, and corrosion inhibitors. It can also be used as a catalyst for the manufacture of polyurethane and a curing agent for epoxy resins. For example, when 1-methylimidazole is added to an aqueous diethylenetriamine (DETA) solution, high CO2 loading can be achieved through phase separation of the absorbent during CO2 absorption[1]. | Preparation | 1-Methylimidazole is prepared mainly by two routes industrially. The main one is acid-catalysed methylation of imidazole by methanol. The second method involves the Radziszewski reaction from glyoxal, formaldehyde, and a mixture of ammonia and methylamine. (CHO)2 + CH2O + CH3NH2 + NH3 → H2C2N(NCH3)CH + 3 H2O The compound can be synthesized on a laboratory scale by methylation of imidazole at the pyridine-like nitrogen and subsequent deprotonation. Similarly, 1-methylimidazole may be synthesized by first deprotonating imidazole to form a sodium salt followed by methylation. H2C2N(NH)CH + CH3I → [H2C2(NH)(NCH3)CH]I [H2C2(NH)(NCH3)CH]I + NaOH → H2C2N(NCH3)CH + H2O + NaI | Definition | ChEBI: 1-methyl-1H-imidazole is a 1H-imidazole having a methyl substituent at the N-1 position. It is a metabolite of 1-methyl-2-thioimidazole (methimazole). It inhibits bone resorption. | General Description | This product has been enhanced for catalysis. 1-Methylimidazole is a derivative of imidazole that is utilized in the manufacture of such classes of items as pharmaceuticals, pesticides, ion-exchange resins, dye intermediates, textile auxiliaries, photographic chemicals, and corrosion inhibitors. It is also used as a catalyst for manufacturing polyurethanes and a curing agent for epoxy resins. | Flammability and Explosibility | Not classified | Purification Methods | Dry it with sodium metal and then distil it. Store it at 0o under dry argon. The picrate has m 159.5-160.5o (from H2O). [Beilstein 23 III/IV 568.] | References | [1] You J, et al. Effect of 1-Methylimidazole on CO2 Absorption by Diethylenetriamine (DETA) Aqueous Solutions. Chemical Engineering & Technology, 2017; 40: 2238-2242. |
| 1-Methylimidazole Preparation Products And Raw materials |
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