NCB-0846 manufacturers
- NCB-0846
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- $1.00 / 1KG
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2019-12-27
- CAS:1792999-26-8
- Min. Order: 1KG
- Purity: 97%-99.9%
- Supply Ability: 100kg
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| | NCB-0846 Basic information |
| Product Name: | NCB-0846 | | Synonyms: | NCB-0846;CS-2514;NCB0846;NCB 0846;cis-4-[[2-(1H-Benzimidazol-6-ylamino)-8-quinazolinyl]oxy]-cyclohexanol;Cyclohexanol, 4-[[2-(1H-benzimidazol-6-ylamino)-8-quinazolinyl]oxy]-, cis-;cis-4-((2-((1H-Benzo[d]imidazol-6-yl)amino)quinazolin-8-yl)oxy)cyclohexanol;Wnt,MAPK Kinase Kinase Kinase,NCB0846,Inhibitor,inhibit,MAP4K,NCB-0846;Epoxiconazolet Impurity 5 | | CAS: | 1792999-26-8 | | MF: | C21H21N5O2 | | MW: | 375.42 | | EINECS: | | | Product Categories: | | | Mol File: | 1792999-26-8.mol |  |
| | NCB-0846 Chemical Properties |
| Boiling point | 726.2±70.0 °C(Predicted) | | density | 1.415±0.06 g/cm3(Predicted) | | storage temp. | -20°C Freezer | | solubility | DMSO (Slightly), Methanol (Slightly) | | form | Solid | | pka | 12.87±0.30(Predicted) | | color | Off-White to Light Yellow | | CAS DataBase Reference | 1792999-26-8 |
| | NCB-0846 Usage And Synthesis |
| Uses | cis-4-?[[2-?(1H-?Benzimidazol-?6-?ylamino)?-?8-?quinazolinyl]?oxy]?-?cyclohexanol inhibits Traf2 and Nck-interacting protein kinase (TNIK). TNIK is involved with Canonical Wnt/b-catenin signalling, which has regulatory roles in maintaining intestinal stem cells and aberration in this pathway has been implicated in colorectal carcinogenesis. TNIK is a therapeutic target. |
| | NCB-0846 Preparation Products And Raw materials |
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