IRL-1620 manufacturers
- Sovateltide
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- $70.00 / 1kg
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2024-05-10
- CAS:142569-99-1
- Min. Order: 10kg
- Purity: 0.99
- Supply Ability: 20tons
- IRL-1620
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- $7.00 / 1KG
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2020-02-14
- CAS: 142569-99-1
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 100kg
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| | IRL-1620 Basic information |
| Product Name: | IRL-1620 | | Synonyms: | IRL-1620, HUMAN;IRL-1620;ENDOTHELIN-1(8-21), N-SUC-[GLU9, ALA11,15];N-SUC-[GLU9, ALA11,15]ENDOTHELIN-I (8-21);N-SUCCINYL-[GLU9, ALA11,15]-ENDOTHELIN, 8-21;SUC-ASP-GLU-GLU-ALA-VAL-TYR-PHE-ALA-HIS-LEU-ASP-ILE-ILE-TRP;SUC-ASP-GLU-GLU-ALA-VAL-TYR-PHE-ALA-HIS-LEU-ASP-ILE-ILE-TRP-OH;SUCCINYL-(GLU9,ALA11,15)-ENDOTHELIN-1 (8-21) | | CAS: | 142569-99-1 | | MF: | C86H117N17O27 | | MW: | 1820.95 | | EINECS: | | | Product Categories: | Endothelin receptor | | Mol File: | 142569-99-1.mol |  |
| | IRL-1620 Chemical Properties |
| Boiling point | 2096.6±65.0 °C(Predicted) | | density | 1.347±0.06 g/cm3(Predicted) | | storage temp. | −20°C | | solubility | Soluble in DMSO | | form | powder | | pka | 3.39±0.10(Predicted) | | color | white | | Water Solubility | Soluble in water (0.5 mg/ml) | | Sequence | Suc-Asp-Glu-Glu-Ala-Val-Tyr-Phe-Ala-His-Leu-Asp-Ile-Ile-Trp-OH |
| | IRL-1620 Usage And Synthesis |
| Biological Activity | IRL-1620 is a potent and selective endorphin receptor (endothelin receptor) type B agonist with a Ki of 16 pM. | | in vitro | IRL-1620 is the most potent and specific ligand for the ETB receptor (K i ETA/ K i ETB=120,000) as judged by the K i values for ETA (19 μM) and ETB (16 PM) receptors. IRL-1620 is 60 times more selective for the ETB receptor than ET-3 (K i ETA /K i ETB=1,900). | | target | IC50: 16 pM (Endothelin receptor B), 19 μM (Endothelin receptor A) | | storage | -20°C (desiccate) |
| | IRL-1620 Preparation Products And Raw materials |
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