| Company Name: |
3B Pharmachem (Wuhan) International Co.,Ltd.
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| Tel: |
821-50328103-801 18930552037 |
| Email: |
3bsc@sina.com |
| Products Intro: |
Product Name:R-96544 hydrochloride;(2R,4R)-5-[2-[2-[2-(3-Methoxyphenyl)ethyl]phenoxy]ethyl]-1-Methyl-3-pyrrolidinolhydrochloride
CAS:167144-79-8
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g
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| Company Name: |
EMMX Biotechnology LLC
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| Tel: |
888-539-0666 |
| Email: |
info@emmx.com |
| Products Intro: |
Product Name:R-96544 hydrochloride
CAS:167144-79-8
Purity:98% HPLC Package:5mg;10mg;25mg;50mg;100mg;250mg;500mg;1g
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| Company Name: |
Energy Chemical
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| Tel: |
021-58432009 400-005-6266 |
| Email: |
marketing1@energy-chemical.com |
| Products Intro: |
Product Name:R-96544Hydrochloride
CAS:167144-79-8
Purity:NULL Package:10mg;25mg Remarks:NULL
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| | (3R,5R)-5-[2-[2-[2-(3-METHOXYPHENYL)ETHYL]PHENOXY]ETHYL]-1-METHYL-3-PYRROLIDINOL HYDROCHLORIDE Basic information |
| | (3R,5R)-5-[2-[2-[2-(3-METHOXYPHENYL)ETHYL]PHENOXY]ETHYL]-1-METHYL-3-PYRROLIDINOL HYDROCHLORIDE Chemical Properties |
| Boiling point | 484.5±40.0 °C(Predicted) | | density | 1.109±0.06 g/cm3(Predicted) | | storage temp. | Store at RT | | solubility | <39.19mg/ml in Water; <39.19mg/ml in DMSO | | pka | 14.87±0.40(Predicted) |
| | (3R,5R)-5-[2-[2-[2-(3-METHOXYPHENYL)ETHYL]PHENOXY]ETHYL]-1-METHYL-3-PYRROLIDINOL HYDROCHLORIDE Usage And Synthesis |
| Uses | R-96544 Hydrochloride is a the active form of a novel 5-HT2A receptor antagonist R-102444. It inhibits the platelet aggregation induced by serotonin (5-hydroxytryptamine, 5-HT). | | Definition | ChEBI: (3R,5R)-5-[2-[2-[2-(3-methoxyphenyl)ethyl]phenoxy]ethyl]-1-methyl-3-pyrrolidinol is a stilbenoid. | | Biological Activity | Potent, selective 5-HT 2 receptor antagonist; displays some selectivity for 5-HT 2A receptors (K i = 1.6 nM). IC 50 values are 2.2, 310, 2400, 3700, > 5000 and > 5000 nM for 5-HT 2 , a 1 -adrenergic, D 2 dopamine, 5-HT 1 , 5-HT 3 and b-adrenergic receptors respectively. Inhibits 5-HT-induced platelet aggregation and pressor responses in vivo . |
| | (3R,5R)-5-[2-[2-[2-(3-METHOXYPHENYL)ETHYL]PHENOXY]ETHYL]-1-METHYL-3-PYRROLIDINOL HYDROCHLORIDE Preparation Products And Raw materials |
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