| Company Name: |
3B Pharmachem (Wuhan) International Co.,Ltd.
|
| Tel: |
821-50328103-801 18930552037 |
| Email: |
3bsc@sina.com |
| Products Intro: |
Product Name:AC-IETD-AFC
CAS:211990-57-7
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g
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| Company Name: |
GL Biochem (Shanghai) Ltd
|
| Tel: |
21-61263452 13641803416 |
| Email: |
ymbetter@glbiochem.com |
| Products Intro: |
Product Name:Caspase 8 Substrate 1f, fluorogenic;Ac-IETD-AFC
CAS:211990-57-7
Purity:95% HPLC 98% HPLC Package:1mg,5mg,10mg,25mg,100mg,1g,10g
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AC-IETD-AFC manufacturers
- AC-IETD-AFC
-
- $1.00 / 1g
-
2020-03-06
- CAS:211990-57-7
- Min. Order: 1g
- Purity: ≥98%
- Supply Ability: g/kg/Ton
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| | AC-IETD-AFC Basic information |
| Product Name: | AC-IETD-AFC | | Synonyms: | CASPASE 8 SUBSTRATE 1F, FLUOROGENIC;CASPASE-8 FLUOROGENIC SUBSTRATE;GRANZYME B SUBSTRATE I, COLORIMETRIC;AC-IETD-AFC;AC-ILE-GLU-THR-ASP-7-AMINO-4-TRIFLUORO-METHYLCOUMARIN;AC-ILE-GLU-THR-ASP-AFC;N-ACETYL-ILE-GLU-THR-ASP-(7-AMINO-4-TRIFLUOROMETHYLCOUMARIN);N-ACETYL-ILE-GLU-THR-ASP-7-AMINO-4-TRIFLUOROMETHYLCOUMARIN AFC | | CAS: | 211990-57-7 | | MF: | C31H38F3N5O12 | | MW: | 729.65 | | EINECS: | | | Product Categories: | Caspase/Related Products;peptide;Caspases/Apoptosis | | Mol File: | 211990-57-7.mol |  |
| | AC-IETD-AFC Chemical Properties |
| Boiling point | 1113.8±65.0 °C(Predicted) | | density | 1.437±0.06 g/cm3(Predicted) | | storage temp. | -20°C | | solubility | Soluble in DMSO | | pka | 4.09±0.10(Predicted) | | form | Lyophilized powder | | color | White to off-white |
| | AC-IETD-AFC Usage And Synthesis |
| Uses | N-Acetyl-Ile-Glu-Thr-Asp-7-amino-4-(trifluoromethyl)coumarin is a fluorogenic substrate for caspases -6, -8, and -10. The IETD sequence is based on the procaspase-3 cleavage site. Residues 172-175 of procaspase-3 are cleaved during apoptosis to produce the p12 subunit and a p20 peptide that is further cleaved to form the p17 subunit of mature caspase 3. | | Uses | Ac-IETD-AFC is a fluorogenic substrate for caspase-8/caspase-3 processing enzyme and granzyme B. It is also a substrate for caspase-10. The IETD sequence is based on caspase-3 proenzyme cleavage site. |
| | AC-IETD-AFC Preparation Products And Raw materials |
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