| Company Name: |
Shanghai Hongye Biotechnology Co. Ltd
|
| Tel: |
400-9205774 |
| Email: |
sales@glpbio.cn |
| Products Intro: |
Product Name:6α-Prostaglandin I1
CAS:62777-90-6
Purity:>98% Package:1mg;10mg;50mg;100mg;
|
| Company Name: |
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
|
| Tel: |
18818260767 |
| Email: |
sales@chemegen.com |
| Products Intro: |
Product Name:6α-Prostaglandin I1
CAS:62777-90-6
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
|
| Company Name: |
Shanghai Yifei Biotechnology Co. , Ltd.
|
| Tel: |
021-65675885 18964387627 |
| Email: |
customer_service@efebio.com |
| Products Intro: |
Product Name:6α-Prostaglandin I1
CAS:62777-90-6
Purity:99% Package:1mg;5mg;10mg
|
| Company Name: |
TargetMol Chemicals Inc.
|
| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:6α-Prostaglandin I1
CAS:62777-90-6
Purity:详情请点击官网 Package:1 mg
|
|
| | 5,6ALPHA-DIHYDRO PGI2 Basic information |
| Product Name: | 5,6ALPHA-DIHYDRO PGI2 | | Synonyms: | 5,6ALPHA-DIHYDRO PGI2;6R,9ALPHA-EPOXY-11ALPHA,15S-DIHYDROXY-PROST-13E-EN-1-OIC ACID;6ALPHA-PROSTAGLANDIN I1;(6R,13E,15S)-6,9α-Epoxy-11α,15-dihydroxyprost-13-en-1-oic acid;6α-Prostaglandin I1;RJADQDXZYFCVHV-WDONHGPHSA-N;Prost-13-en-1-oic acid, 6,9-epoxy-11,15-dihydroxy-, (6R,9α,11α,13E,15S)- (9CI);6α-Prostaglandin I1 | | CAS: | 62777-90-6 | | MF: | C20H34O5 | | MW: | 354.48 | | EINECS: | | | Product Categories: | | | Mol File: | 62777-90-6.mol |  |
| | 5,6ALPHA-DIHYDRO PGI2 Chemical Properties |
| storage temp. | Store at -20°C | | solubility | DMF: >10 (from (6b-PGI1); DMSO: >5 (from (6b-PGI1); Ethanol: >20 mg/ml (from (6b-PGI1); PBS pH 7.2: >80 μg (from (6b-PGI1) | | form | A crystalline solid |
| | 5,6ALPHA-DIHYDRO PGI2 Usage And Synthesis |
| Description | 6α-Prostaglandin I1 (6α-PGI1) is a stable Prostaglandin I2 (PGI2) analog resistant to hydrolysis in aqueous solutions. 6α-PGI1 promotes cyclic AMP accumulation in human thyroid slices and cells in a concentration dependent manner. However, it is about 10-fold less potent than the β-isomer and 100-fold less potent than PGI2 in eliciting the response.1 6α-PGI1 exhibits an IC50 of 350 ng/ml for inhibition of ADP-induced platelet aggregation, which is nearly 900-fold higher than that observed for PGI2 (0.4 ng/ml).2 | | Definition | ChEBI: 6alpha-Prostaglandin I1 is a prostaglandins I. | | References | 1. Patrono, C., Rotella, C.M., Toccafondi, R.S., et al. Prostacyclin stimulates the adenylate cyclase system of human thyroid tissue Prostaglandins 22(1),105-115(1981).
2. Whittle, B.J.R., and Moncada, S. Prostacyclin and its analogues for the therapy of thromboembolic disorders Adv. Exp. Med. Biol. 164,193-209(1984). |
| | 5,6ALPHA-DIHYDRO PGI2 Preparation Products And Raw materials |
|