Company Name: |
Shanghai Hongye Biotechnology Co. Ltd
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Tel: |
400-9205774 |
Email: |
sales@glpbio.cn |
Products Intro: |
Product Name:6α-Prostaglandin I1 CAS:62777-90-6 Purity:>98% Package:1mg;10mg;50mg;100mg;
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Company Name: |
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
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Tel: |
18818260767 |
Email: |
sales@chemegen.com |
Products Intro: |
Product Name:6α-Prostaglandin I1 CAS:62777-90-6 Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
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Company Name: |
Shanghai Yifei Biotechnology Co. , Ltd.
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Tel: |
021-65675885 18964387627 |
Email: |
customer_service@efebio.com |
Products Intro: |
Product Name:6α-Prostaglandin I1 CAS:62777-90-6 Purity:99% Package:1mg;5mg;10mg
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Company Name: |
TargetMol Chemicals Inc.
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Tel: |
15002134094 |
Email: |
marketing@targetmol.cn |
Products Intro: |
Product Name:6α-Prostaglandin I1 CAS:62777-90-6 Purity:详情请点击官网 Package:1 mg
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| 5,6ALPHA-DIHYDRO PGI2 Basic information |
Product Name: | 5,6ALPHA-DIHYDRO PGI2 | Synonyms: | 5,6ALPHA-DIHYDRO PGI2;6R,9ALPHA-EPOXY-11ALPHA,15S-DIHYDROXY-PROST-13E-EN-1-OIC ACID;6ALPHA-PROSTAGLANDIN I1;(6R,13E,15S)-6,9α-Epoxy-11α,15-dihydroxyprost-13-en-1-oic acid;6α-Prostaglandin I1;RJADQDXZYFCVHV-WDONHGPHSA-N;Prost-13-en-1-oic acid, 6,9-epoxy-11,15-dihydroxy-, (6R,9α,11α,13E,15S)- (9CI);6α-Prostaglandin I1 | CAS: | 62777-90-6 | MF: | C20H34O5 | MW: | 354.48 | EINECS: | | Product Categories: | | Mol File: | 62777-90-6.mol | ![5,6ALPHA-DIHYDRO PGI2 Structure](CAS/GIF/62777-90-6.gif) |
| 5,6ALPHA-DIHYDRO PGI2 Chemical Properties |
storage temp. | Store at -20°C | solubility | DMF: >10 (from (6b-PGI1); DMSO: >5 (from (6b-PGI1); Ethanol: >20 mg/ml (from (6b-PGI1); PBS pH 7.2: >80 μg (from (6b-PGI1) | form | A crystalline solid |
| 5,6ALPHA-DIHYDRO PGI2 Usage And Synthesis |
Description | 6α-Prostaglandin I1 (6α-PGI1) is a stable Prostaglandin I2 (PGI2) analog resistant to hydrolysis in aqueous solutions. 6α-PGI1 promotes cyclic AMP accumulation in human thyroid slices and cells in a concentration dependent manner. However, it is about 10-fold less potent than the β-isomer and 100-fold less potent than PGI2 in eliciting the response.1 6α-PGI1 exhibits an IC50 of 350 ng/ml for inhibition of ADP-induced platelet aggregation, which is nearly 900-fold higher than that observed for PGI2 (0.4 ng/ml).2 | Definition | ChEBI: 6alpha-Prostaglandin I1 is a prostaglandins I. | References | 1. Patrono, C., Rotella, C.M., Toccafondi, R.S., et al. Prostacyclin stimulates the adenylate cyclase system of human thyroid tissue Prostaglandins 22(1),105-115(1981). 2. Whittle, B.J.R., and Moncada, S. Prostacyclin and its analogues for the therapy of thromboembolic disorders Adv. Exp. Med. Biol. 164,193-209(1984). |
| 5,6ALPHA-DIHYDRO PGI2 Preparation Products And Raw materials |
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