Company Name: |
3B Pharmachem (Wuhan) International Co.,Ltd.
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Tel: |
821-50328103-801 18930552037 |
Email: |
3bsc@sina.com |
Products Intro: |
Product Name:AH 11110 hydrochloride;4-IMino-1-(2-phenylphenoxy)-4-piperidinebutan-2-olhydrochloride CAS:179388-65-9 Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g
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Company Name: |
EMMX Biotechnology LLC
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Tel: |
888-539-0666 |
Email: |
info@emmx.com |
Products Intro: |
Product Name:AH 11110 hydrochloride CAS:179388-65-9 Purity:98% HPLC Package:5mg;10mg;25mg;50mg;100mg;250mg;500mg;1g
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Company Name: |
BOC Sciences
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Tel: |
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Email: |
info@bocsci.com |
Products Intro: |
Product Name:AH 11110 hydrochloride CAS:179388-65-9 Purity:≥98% by HPLC Remarks:The hydrochloride salt form of AH 11110, which is an α1B-adrenoceptor ligand and has been found to exhibit interaction with α1-adrenoceptors as well as α2-adrenoceptors.
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Company Name: |
Energy Chemical
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Tel: |
021-58432009 400-005-6266 |
Email: |
marketing1@energy-chemical.com |
Products Intro: |
Product Name:AH 11110 >98% (HPLC), solid CAS:179388-65-9 Purity:>98% (HPLC), solid Package:50mg Remarks:NULL
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| AH 11110 HYDROCHLORIDE Basic information |
Product Name: | AH 11110 HYDROCHLORIDE | Synonyms: | 1-[BIPHENYL-2-YLOXY]-4-IMINO-4-PIPERIDIN-1-YL-BUTAN-2-OL HYDROCHLORIDE;4-IMINO-1-(2-PHENYLPHENOXY)-4-PIPERIDINEBUTAN-2-OL HYDROCHLORIDE;AH 11110 HYDROCHLORIDE;AH 11110;AH11110HCl;AH 11110 >98% (HPLC), solid | CAS: | 179388-65-9 | MF: | C21H27ClN2O2 | MW: | 374.91 | EINECS: | | Product Categories: | | Mol File: | 179388-65-9.mol | |
| AH 11110 HYDROCHLORIDE Chemical Properties |
storage temp. | −20°C | solubility | H2O: ~2.5 mg/mL, soluble | form | solid | color | slightly yellow | Water Solubility | Soluble to 25 mM in water |
| AH 11110 HYDROCHLORIDE Usage And Synthesis |
Uses | AH 11110 Hydrochloride is an α1B-adrenoceptor selective drug. AH 11110 Hydrochloride has been shown to interact with α1-adrenoceptors as well as α2-adrenoceptors. | Biological Activity | A subtype-selective ligand for the α 1B -adrenoceptor. The pK i values for binding to rat fibroblast cell membranes expressing α 1B (hamster), α 1A (bovine) and α 1D (rat) are 7.1, 5.59, and 5.68 respectively. Appears to be non-selective between α 1 subtypes and α 2 receptors in smooth muscle preparations. | references | [1]. erami c, zhang h, ho jg, et al. alpha(1)-adrenoceptor stimulation directly induces growth of vascular wall in vivo. am j physiol heart circ physiol, 2002, 283(4): h1577-1587. [2]. eltze m, könig h, ullrich b, et al. failure of ah11110a to functionally discriminate between alpha(1)-adrenoceptor subtypes a, b and d or between alpha(1)- and alpha(2)-adrenoceptors. eur j pharmacol, 2001, 415(2-3): 265-276. |
| AH 11110 HYDROCHLORIDE Preparation Products And Raw materials |
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