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| | 3-Bromo-2-fluorobenzoic acid Basic information |
| | 3-Bromo-2-fluorobenzoic acid Chemical Properties |
| Melting point | 168 °C | | Boiling point | 298.2±25.0 °C(Predicted) | | density | 1.789±0.06 g/cm3(Predicted) | | storage temp. | Sealed in dry,Room Temperature | | form | powder to crystal | | pka | 2.88±0.10(Predicted) | | color | White to Light yellow | | InChIKey | UVKURTLVTLRSSM-UHFFFAOYSA-N | | CAS DataBase Reference | 161957-56-8(CAS DataBase Reference) |
| Hazard Codes | Xi | | Risk Statements | 36 | | Safety Statements | 26 | | HazardClass | IRRITANT | | HS Code | 2916399090 |
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ALFA
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| | 3-Bromo-2-fluorobenzoic acid Usage And Synthesis |
| Chemical Properties | Off-white powder | | Uses | 3-Bromo-2-fluorobenzoic acid is used as a reagent to synthesize Dabrafenib, an inhibitor of BRAF kinase that is used to treat BRAF V600-mutation positive carcinoma. BRAF is a gene that mediates cell growth and is activated by mutations caused by cancer. 3-Bromo-2-fluorobenzoic acid is also used as a reagent to prepare Alkynlphenoxyacetic acid receptor agonists, compounds that can be potentially used for the treatment of allergic inflammatory diseases (such as allergic rhinitis). |
| | 3-Bromo-2-fluorobenzoic acid Preparation Products And Raw materials |
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